Cart
sales@molnova.com
SC-560
CAS No. 188817-13-2
SC-560( SC-560 | SC 560 | SC560 )
Catalog No. M17399 CAS No. 188817-13-2
SC-560 is a member of the diaryl heterocycle class of cyclooxygenase (COX) inhibitors.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 30 | In Stock |
|
| 5MG | 47 | In Stock |
|
| 10MG | 84 | In Stock |
|
| 25MG | 178 | In Stock |
|
| 50MG | 227 | In Stock |
|
| 100MG | 291 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameSC-560
-
NoteResearch use only, not for human use.
-
Brief DescriptionSC-560 is a member of the diaryl heterocycle class of cyclooxygenase (COX) inhibitors.
-
DescriptionSC-560 is a potent, orally active and selective inhibitor of COX-1. Using human recombinant enzymes, the IC50 value for SC-560 with respect to COX-1 is 9 nM, while the corresponding IC50 value for COX-2 is 6.3 μM.1 Thus, SC-560 shows 700-fold selectivity for the COX-1 enzyme.
-
In Vitro——
-
In Vivo——
-
SynonymsSC-560 | SC 560 | SC560
-
PathwayOthers
-
TargetOther Targets
-
RecptorCOX-1| COX-2
-
Research AreaCancer|Inflammation/Immunology
-
Indication——
Chemical Information
-
CAS Number188817-13-2
-
Formula Weight352.74
-
Molecular FormulaC17H12ClF3N2O
-
Purity>98% (HPLC)
-
SolubilityDMSO : ≥ 100 mg/mL 283.49 mM; H2O : < 0.1 mg/mL
-
SMILESCOc1ccc(cc1)n1c(cc(n1)C(F)(F)F)c1ccc(cc1)Cl
-
Chemical Name5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluoromethyl)-1H-pyrazole
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Smith CJ, et al. Pharmacological analysis of cyclooxygenase-1 in inflammation. Proc Natl Acad Sci U S A. 1998 Oct 27;95(22):13313-8.
molnova catalog
related products
-
Prolactin Releasing ...
Prolactin Releasing Peptide (1-31), human is a high affinity GPR10 ligand that cause the release of the prolactin. Human and rat Prolactin Releasing Peptide (1-31) binds to GPR10 with Kis of 1.03 and 0.33 nM, respectively.Prolactin-releasing peptide is a specific prolactin releasing peptide.
-
Dehydromiltirone
Dehydromiltirone has antioxidant activity, it shows significant anti-neuroinflammatory effects through inhibiting PI3K/Akt phosphorylation and then inhibiting NF-κB signaling pathway.
-
Taraxeryl acetate
Taraxeryl acetate shows the significant antiviral activity against herpes simplex virus (type II). It has less effect on cell cycle arrest and apoptosis of AGS cells than taraxerol.
