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CPI-1189
CAS No. 183619-38-7
CPI-1189( CPI-1189 | REN-1189 | REN-1654 | REN1189 )
Catalog No. M17393 CAS No. 183619-38-7
REN-1189 is a TNF-a release inhibitor potentially for the treatment of sciatica and postherpetic neuralgia.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 29 | In Stock |
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| 10MG | 36 | In Stock |
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| 25MG | 79 | In Stock |
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| 50MG | 127 | In Stock |
|
| 100MG | 211 | In Stock |
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| 200MG | 310 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCPI-1189
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NoteResearch use only, not for human use.
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Brief DescriptionREN-1189 is a TNF-a release inhibitor potentially for the treatment of sciatica and postherpetic neuralgia.
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DescriptionREN-1189 is a TNF-a release inhibitor potentially for the treatment of sciatica and postherpetic neuralgia.
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In VitroCell Viability Assay Cell Line:SH-SY5Y oncentration:10, 30, 100, 300 nM Incubation Time:1 h Result:Alleviated OGDR-induced cytotoxicity in a concentration-dependent manner.Apoptosis Analysis Cell Line:SH-SY5Y Concentration:100 nM Incubation Time:1 h Result:Inhibited OGDR-induced caspase-3/-9 activation and ssDNA accumulation.Attenuated OGDR-induced apoptosis activation.
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In Vivo——
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SynonymsCPI-1189 | REN-1189 | REN-1654 | REN1189
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PathwayOthers
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TargetOther Targets
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RecptorTNF-α
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Research Area——
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Indication——
Chemical Information
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CAS Number183619-38-7
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Formula Weight234.3
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Molecular FormulaC13H18N2O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (426.82 mM)
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SMILESCC(=O)Nc1ccc(cc1)C(=O)NC(C)(C)C
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Chemical Name4-acetamido-N-(tert-butyl)benzamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Bjugstad KB,et al. Preventive actions of a synthetic antioxidant in a novel animal model of AIDS dementia. Brain Res. 1998 Jun 8;795(1-2):349-57.
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