Diroximel Fumarete
CAS No. 1577222-14-0
Diroximel Fumarete( Diroximel fumarate | ALKS8700 | ALKS 8700 | ALKS-8700 )
Catalog No. M17336 CAS No. 1577222-14-0
Diroximel fumarate, a prodrug of monomethyl fumarate in a controlled-release formulation, rapidly and potently converts to MMF in the body.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 50 | In Stock |
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| 2MG | 30 | In Stock |
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| 5MG | 50 | In Stock |
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| 10MG | 73 | In Stock |
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| 25MG | 128 | In Stock |
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| 50MG | 193 | In Stock |
|
| 100MG | 312 | In Stock |
|
| 200MG | 440 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameDiroximel Fumarete
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NoteResearch use only, not for human use.
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Brief DescriptionDiroximel fumarate, a prodrug of monomethyl fumarate in a controlled-release formulation, rapidly and potently converts to MMF in the body.
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DescriptionDiroximel fumarate, also known as ALKS-8700, is a prodrug of monomethyl fumarate in a controlled-release formulation that rapidly and efficiently converts to MMF in the body.
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In Vitro——
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In Vivo——
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SynonymsDiroximel fumarate | ALKS8700 | ALKS 8700 | ALKS-8700
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number1577222-14-0
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Formula Weight255.22
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Molecular FormulaC11H13NO6
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Purity>98% (HPLC)
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SolubilityDMSO : 125 mg/mL. 489.77 mM;
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SMILESCOC(=O)/C=C/C(=O)OCCN1C(=O)CCC1=O
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Chemical Name2-(2,5-dioxopyrrolidin-1-yl)ethyl methyl fumarate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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RMC-6291
RMC-6291 is an orally active, covalent inhibitor of KRAS G12C (ON) that forms a tri-complex within tumor cells between KRAS G12C (ON) and cyclophilin A (CypA), thereby preventing KRAS G12C (ON) from signaling via steric blockade of RAS effector binding and eliciting deep and durable suppression of RAS pathway activity in KRAS G12C tumor models .
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Forsythoside E
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Schisantherin D
Schisantherin D is a dibenzocyclooctadiene lignan isolated from the fruit of Schisandra sphenanthera. Schisantherin D shows anti-HIV replication activities with an EC50 of 0.5 μg/mL. Schisantherin D inhibits endothelin receptor B (ETBR) and has hepatoprotective effects.
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