GSK2200150A

CAS No. 1443138-53-1

GSK2200150A( GSK2200150A | GSK-2200150A | GSK 2200150A )

Catalog No. M17300 CAS No. 1443138-53-1

GSK2200150A, identified by high-throughput screening (HTS) campaign, is an anti-tuberculosis (TB) agent.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 29 In Stock
10MG 36 In Stock
25MG 69 In Stock
50MG 110 In Stock
100MG 164 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    GSK2200150A
  • Note
    Research use only, not for human use.
  • Brief Description
    GSK2200150A, identified by high-throughput screening (HTS) campaign, is an anti-tuberculosis (TB) agent.
  • Description
    GSK2200150A is an antimycobacterial agent against Mycobacterium tuberculosis and Mycobacterium bovis BCG.
  • In Vitro
    GSK2200150A is a novel antimycobacterial agent against Mycobacterium tuberculosis.The activities of GSK2200150A containing the spirocycle core are determined against the virulent M.tuberculosis strain (H37Rv) with MIC of 0.38 μM.
  • In Vivo
    ——
  • Synonyms
    GSK2200150A | GSK-2200150A | GSK 2200150A
  • Pathway
    JAK/STAT Signaling
  • Target
    Pim
  • Recptor
    Bacterial
  • Research Area
    Infection
  • Indication
    ——

Chemical Information

  • CAS Number
    1443138-53-1
  • Formula Weight
    357.47
  • Molecular Formula
    C20H23NO3S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : ≥ 83.33 mg/mL. 233.11 mM
  • SMILES
    C4COC3(CCN(Cc1ccc2OCCOc2c1)CC3)c5ccsc45
  • Chemical Name
    1-[(2,3-Dihydro-1,4-benzodioxin-6-yl)methyl]-6',7'-dihydro-spiro[piperidine-4,4'-[4H]thieno[3,2-c]pyran]

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.?Badiola KA, et al. Efficient Synthesis and Anti-Tubercular Activity of a Series of Spirocycles: An Exercise in OpenScience. PLoS One. 2014 Dec 10;9(12):e111782.
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