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HG-14-10-04
CAS No. 1356962-34-9
HG-14-10-04( HG-14-10-04 )
Catalog No. M17255 CAS No. 1356962-34-9
HG-14-10-04 is a potent and specific ALK inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 113 | In Stock |
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| 5MG | 93 | In Stock |
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| 10MG | 155 | In Stock |
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| 25MG | 235 | In Stock |
|
| 50MG | 299 | In Stock |
|
| 100MG | 423 | In Stock |
|
| 200MG | 609 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameHG-14-10-04
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NoteResearch use only, not for human use.
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Brief DescriptionHG-14-10-04 is a potent and specific ALK inhibitor.
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DescriptionHG-14-10-04 is a novel potent and specific ALK inhibitor.
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In VitroHG-14-10-04 (example 10) has inhibitory activity against ALK kinase with an IC50 of 20 nM.HG-14-10-04 (compound 17b) exhibits kinase inhibitory activity against EGFRLR/TM, EGFR19del/TM/CS and EGFRLR/TM/CS with IC50s of 15.6 nM, 22.6 nM and 124.5 nM, respectively.
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In Vivo——
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SynonymsHG-14-10-04
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PathwayGPCR/G Protein
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TargetLPA Receptor
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RecptorALK
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1356962-34-9
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Formula Weight532.08
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Molecular FormulaC29H34ClN7O
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Purity>98% (HPLC)
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SolubilityDMSO : 13.3 mg/mL. 25.00 mM;
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SMILESCN1CCN(C2CCN(c3ccc(Nc4ncc(Cl)c(c5c[nH]c6c5cccc6)n4)c(OC)c3)CC2)CC1
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Chemical Name[5-Chloro-4-(1H-indol-3-yl)-pyrimidin-2-yl]-{2-methoxy-4-[4-(4-methyl-piperazin-1-yl)-piperidin-1-yl]-phenyl}-amine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.U.S. Pat. Appl. Publ. (2012), US 20120028924 A1
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