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c-Kit-IN-1
CAS No. 1225278-16-9
c-Kit-IN-1( —— )
Catalog No. M17203 CAS No. 1225278-16-9
DCC-2618 is an effective inhibitor of c-Met and c-Kit (IC50s<200 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 76 | In Stock |
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| 5MG | 70 | In Stock |
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| 10MG | 117 | In Stock |
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| 25MG | 236 | In Stock |
|
| 50MG | 365 | In Stock |
|
| 100MG | 598 | In Stock |
|
| 200MG | 823 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Namec-Kit-IN-1
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NoteResearch use only, not for human use.
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Brief DescriptionDCC-2618 is an effective inhibitor of c-Met and c-Kit (IC50s<200 nM).
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DescriptionDCC-2618 is an effective inhibitor of c-Met and c-Kit (IC50s<200 nM).(In Vitro):c-Kit-IN-1 is a c-Kit and c-Met inhibitor extracted from patent 2010051373A1, compound example 45, has an IC50 of <200 nM. c-Kit-IN-1 also inhibits KDR, PDGFR α and β with IC50s of <2 μM, <10 μM and <10 μM, respectively.
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In Vitroc-Kit-IN-1 is a c-Kit and c-Met inhibitor extracted from patent 2010051373A1, compound example 45, has an IC50 of <200 nM. c-Kit-IN-1 also inhibits KDR, PDGFR α and β with IC50s of <2 μM, <10 μM and <10 μM, respectively.
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In Vivo——
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Synonyms——
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PathwayEndocrinology/Hormones
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TargetCaMK
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Recptorc-Kit| c-Met
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1225278-16-9
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Formula Weight489.47
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Molecular FormulaC26H21F2N5O3
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 100 mg/mL. 204.30 mM
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SMILESCn1cc(cn1)c1nccc(c1)Oc1c(cc(c(c1)F)NC(=O)C1(CC1)C(=O)Nc1ccccc1)F
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Daniel L. Flynn, et al. Cyclopropane amides and analogs exhibiting anti-cancer and anti-proliferative activities. WO 2010051373 A1
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