Cart
sales@molnova.com
VU 0357017 hydrochloride
CAS No. 1135242-13-5
VU 0357017 hydrochloride( VU0357017, VU-0357017, VU 0357017, CID 25010775 )
Catalog No. M17152 CAS No. 1135242-13-5
VU 0357017 hydrochloride is highly selective M1 agonists act at an allosteric site to activate the receptor (EC50: 477 ± 172 nM; Pec50: 6.37 ± 0.15).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 35 | In Stock |
|
| 5MG | 32 | In Stock |
|
| 10MG | 50 | In Stock |
|
| 25MG | 93 | In Stock |
|
| 50MG | 147 | In Stock |
|
| 100MG | 217 | In Stock |
|
| 200MG | 322 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameVU 0357017 hydrochloride
-
NoteResearch use only, not for human use.
-
Brief DescriptionVU 0357017 hydrochloride is highly selective M1 agonists act at an allosteric site to activate the receptor (EC50: 477 ± 172 nM; Pec50: 6.37 ± 0.15).
-
DescriptionVU0357017, also known as CID 25010775, is a subtype-selective M1 muscarinic acetylcholine allosteric agonist.
-
In Vitro——
-
In VivoAnimal Model:Male Sprague?Dawley rats (380-420 g) were pretreated with scopolamine Dosage:1, 3, 10 mg/kg Administration:A single i.p.Result:Produced a significant reversal of the scopolamine-induced deficits at a dose of 10 mg/kg.
-
SynonymsVU0357017, VU-0357017, VU 0357017, CID 25010775
-
PathwayOthers
-
TargetOther Targets
-
RecptorM1 mAChR
-
Research AreaNeurological Disease
-
Indication——
Chemical Information
-
CAS Number1135242-13-5
-
Formula Weight369.89
-
Molecular FormulaC18H28ClN3O3
-
Purity>98% (HPLC)
-
SolubilityDMSO : ≥ 33 mg/mL 89.22 mM
-
SMILESCCOC(=O)N1CCC(CC1)NCCNC(=O)c1ccccc1C.Cl
-
Chemical Name4-[[2-[(2-methylbenzoyl)amino]ethyl]amino]-1-piperidinecarboxylic acid ethyl ester, monohydrochloride
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
-
Arnidiol
Arnidiol is a pentacyclic triterpene isolated from Barleria Longiflora Linn FArnidiol has anti-inflammatory activity, it possesses marked inhibitory activity against 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice.
-
Pedalitin 6-O-glucos...
Pedaliin is a bioactive component obtained from the ethanol extract of Sesame (Sesamum indicum L.) leaves (SLs). Pedaliin shows in vitro antioxidant and anti-colon cancer efficacy with radical scavenging activity and ferric reducing antioxidant power (FRAP).
-
[Pyr4] - MBP (4 - 14...
[pGlu4]-Myelin Basic Protein (4-14) is the phosphorylated 4-14 fragment (EKRPSQRSKYL) of myelin basic protein (MBP). [pGlu4]-Myelin Basic Protein (4-14) surrounds the serine residue in position 8 of the myelin basic protein.
