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FtsZ inhibitor C109
CAS No. ——
FtsZ inhibitor C109( Compound 10126109 )
Catalog No. M17105 CAS No. ——
FtsZ inhibitor C109 (Compound 10126109) is a broad spectrum antibacterial compound that inhibits the cell division protein FtsZ, inhibits the FtsZ GTPase activity with IC50 of 8.2 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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Biological Information
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Product NameFtsZ inhibitor C109
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NoteResearch use only, not for human use.
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Brief DescriptionFtsZ inhibitor C109 (Compound 10126109) is a broad spectrum antibacterial compound that inhibits the cell division protein FtsZ, inhibits the FtsZ GTPase activity with IC50 of 8.2 uM.
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DescriptionFtsZ inhibitor C109 (Compound 10126109) is a broad spectrum antibacterial compound that inhibits the cell division protein FtsZ, inhibits the FtsZ GTPase activity with IC50 of 8.2 uM; inhibits both the GTPase and polymerization activities of purified B. cenocepacia FtsZ, prevents divisome formation by altering the localization of the essential cell division protein FtsZ; displayes antibacterial activity against Gram-positive and Gram-negative cystic fibrosis pathogens, including Mycobacterium abscessus, C109 effectively cleared B. cenocepacia infection in the Caenorhabditis elegans model and exhibited additive interactions with clinically relevant antibiotics.
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In Vitro——
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In Vivo——
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SynonymsCompound 10126109
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PathwayGPCR/G Protein
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TargetAntibacterial
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RecptorAntibacterial
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Research Area——
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Indication——
Chemical Information
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CAS Number——
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Formula Weight285.292
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Molecular FormulaC9H7N3O4S2
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Namemethyl 2-((4-nitrobenzo[c][1,2,5]thiadiazol-5-yl)thio)acetate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Hogan AM, et al. Antimicrob Agents Chemother. 2018 Oct 8. pii: AAC.01231-18. doi: 10.1128/AAC.01231-18.
2. Scoffone VC, et al. Front Microbiol. 2015 Aug 5;6:815. doi: 10.3389/fmicb.2015.00815.
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