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Pasireotide ditrifluoroacetate
CAS No. ——
Pasireotide ditrifluoroacetate( SOM230 ditrifluoroacetate )
Catalog No. M16968 CAS No. ——
A potent, stable cyclohexapeptide somatostatin mimic that exhibits unique high-affinity binding to human somatostatin receptors.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NamePasireotide ditrifluoroacetate
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, stable cyclohexapeptide somatostatin mimic that exhibits unique high-affinity binding to human somatostatin receptors.
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DescriptionA potent, stable cyclohexapeptide somatostatin mimic that exhibits unique high-affinity binding to human somatostatin receptors (pKi=8.2/9.0/9.1/<7.0/9.9 for sst1/2/3/4/5, respectively); effectively inhibits GHRH-induced growth hormone release in primary cultures of rat pituitary cells with IC50 of 0.4 nM, also potently suppresses GH secretion in rats.Cushing's Disease Approved.
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In Vitro——
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In Vivo——
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SynonymsSOM230 ditrifluoroacetate
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PathwayGPCR/G Protein
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TargetSomatostatin Receptor
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RecptorSomatostatin Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number——
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Formula Weight1275.253
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Molecular FormulaC62H68F6N10O13
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILES——
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Chemical NameCyclo[(2S)-2-phenylglycyl-D-tryptophyl-L-lysyl-O-(phenylmethyl)-L-tyrosyl-L-phenylalanyl-(4R)-4-[[[(2-aminoethyl)amino]carbonyl]oxy]-L-prolyl], di(trifluoroacetate) (9CI)
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Lewis I, et al. J Med Chem. 2003 Jun 5;46(12):2334-44.
2. Bruns C, et al. Eur J Endocrinol. 2002 May;146(5):707-16.
3. Hofland LJ, et al. Eur J Endocrinol. 2005 Apr;152(4):645-54.
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