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eN-IN-1
CAS No. 95523-13-0
eN-IN-1( 4-Abza | 4Abza | 4 Abza | 4-ABzA | 4ABzA | 4 ABzA | N(6)-(4-aminobenzyl)adenosine )
Catalog No. M16819 CAS No. 95523-13-0
An α,β-Methylene-ADP (AOPCP) derivative, potent, selective ecto-5′-Nucleotidase (eN, CD73) inhibitor with Ki of 29 nM for rat recombinant eN.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 144 | In Stock |
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| 5MG | 113 | In Stock |
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| 10MG | 169 | In Stock |
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| 25MG | 335 | In Stock |
|
| 50MG | 520 | In Stock |
|
| 100MG | 830 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameeN-IN-1
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NoteResearch use only, not for human use.
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Brief DescriptionAn α,β-Methylene-ADP (AOPCP) derivative, potent, selective ecto-5′-Nucleotidase (eN, CD73) inhibitor with Ki of 29 nM for rat recombinant eN.
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DescriptionAn α,β-Methylene-ADP (AOPCP) derivative, potent, selective ecto-5′-Nucleotidase (eN, CD73) inhibitor with Ki of 29 nM for rat recombinant eN; also exhibits dual-action properties toward both A2AR and equilibrative nucleoside transporter 1 (ENT1) with Ki of 27.7 uM and 6.51 nM.
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In Vitro——
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In Vivo——
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Synonyms4-Abza | 4Abza | 4 Abza | 4-ABzA | 4ABzA | 4 ABzA | N(6)-(4-aminobenzyl)adenosine
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PathwayApoptosis
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TargetAdenosine Receptor
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RecptorAdenosine Receptor
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Research AreaNeurological Disease
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Indication——
Chemical Information
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CAS Number95523-13-0
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Formula Weight372.3785
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Molecular FormulaC17H20N6O4
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESOC[C@@H]1[C@H]([C@H]([C@H](N2C=NC3=C(N=CN=C32)NCC4=CC=C(N)C=C4)O1)O)O
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Chemical NameAdenosine, N-[(4-aminophenyl)methyl]-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Bhattarai S, et al. J Med Chem. 2015 Aug 13;58(15):6248-63.
2. Chen JB, et al. ChemMedChem. 2011 Aug 1;6(8):1390-400.
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