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Home - Products - Apoptosis - Adenosine Receptor - eN-IN-1

eN-IN-1

CAS No. 95523-13-0

eN-IN-1( 4-Abza | 4Abza | 4 Abza | 4-ABzA | 4ABzA | 4 ABzA | N(6)-(4-aminobenzyl)adenosine )

Catalog No. M16819 CAS No. 95523-13-0

An α,β-Methylene-ADP (AOPCP) derivative, potent, selective ecto-5′-Nucleotidase (eN, CD73) inhibitor with Ki of 29 nM for rat recombinant eN.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 144 In Stock
5MG 113 In Stock
10MG 169 In Stock
25MG 335 In Stock
50MG 520 In Stock
100MG 830 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    eN-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    An α,β-Methylene-ADP (AOPCP) derivative, potent, selective ecto-5′-Nucleotidase (eN, CD73) inhibitor with Ki of 29 nM for rat recombinant eN.
  • Description
    An α,β-Methylene-ADP (AOPCP) derivative, potent, selective ecto-5′-Nucleotidase (eN, CD73) inhibitor with Ki of 29 nM for rat recombinant eN; also exhibits dual-action properties toward both A2AR and equilibrative nucleoside transporter 1 (ENT1) with Ki of 27.7 uM and 6.51 nM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    4-Abza | 4Abza | 4 Abza | 4-ABzA | 4ABzA | 4 ABzA | N(6)-(4-aminobenzyl)adenosine
  • Pathway
    Apoptosis
  • Target
    Adenosine Receptor
  • Recptor
    Adenosine Receptor
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    95523-13-0
  • Formula Weight
    372.3785
  • Molecular Formula
    C17H20N6O4
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    OC[C@@H]1[C@H]([C@H]([C@H](N2C=NC3=C(N=CN=C32)NCC4=CC=C(N)C=C4)O1)O)O
  • Chemical Name
    Adenosine, N-[(4-aminophenyl)methyl]-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Bhattarai S, et al. J Med Chem. 2015 Aug 13;58(15):6248-63. 2. Chen JB, et al. ChemMedChem. 2011 Aug 1;6(8):1390-400.
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