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MK-8998
CAS No. 953778-58-0
MK-8998( CX-8998 )
Catalog No. M16815 CAS No. 953778-58-0
MK-8998 (CX-8998) is a potent and selective antagonist of the T-type calcium channel for the treatment of schizophrenia.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 33 | In Stock |
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| 5MG | 41 | In Stock |
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| 10MG | 69 | In Stock |
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| 25MG | 126 | In Stock |
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| 50MG | 206 | In Stock |
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| 100MG | 319 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameMK-8998
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NoteResearch use only, not for human use.
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Brief DescriptionMK-8998 (CX-8998) is a potent and selective antagonist of the T-type calcium channel for the treatment of schizophrenia.
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DescriptionMK-8998 (CX-8998) is a potent and selective antagonist of the T-type calcium channel for the treatment of schizophrenia.; does not block D2, 5HT2a, muscarinic, or histaminic receptors; has the potential for a substantially improved side effect profile compared with currently available atypical antipsychotics.Schizophrenia Phase 2 Clinical.
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In Vitro——
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In Vivo——
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SynonymsCX-8998
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PathwayGPCR/G Protein
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TargetCalcium Channel
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RecptorCalcium Channel
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Research AreaNeurological Disease
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IndicationSchizophrenia
Chemical Information
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CAS Number953778-58-0
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Formula Weight380.4040296
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Molecular FormulaC20H23F3N2O2
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESCC(C)C1=CC=C(CC(N[C@H](C)C2=NC=C(OCC(F)(F)F)C=C2)=O)C=C1
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Chemical NameBenzeneacetamide, 4-(1-methylethyl)-N-[(1R)-1-[5-(2,2,2-trifluoroethoxy)-2-pyridinyl]ethyl]-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Egan MF, et al. Hum Psychopharmacol. 2013 Mar;28(2):124-33.
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