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ARRY380
CAS No. 937265-83-3
ARRY380( ARRY-380 analog | ONT380 analog | ONT 380 analog | ONT-380 analog )
Catalog No. M16714 CAS No. 937265-83-3
ARRY-380 is a potent and selective HER2 inhibitor with IC50 of 8 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 84 | In Stock |
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| 2MG | 40 | In Stock |
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| 5MG | 65 | In Stock |
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| 10MG | 106 | In Stock |
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| 25MG | 180 | In Stock |
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| 50MG | 261 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameARRY380
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NoteResearch use only, not for human use.
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Brief DescriptionARRY-380 is a potent and selective HER2 inhibitor with IC50 of 8 nM.
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DescriptionARRY-380 is a potent and selective HER2 inhibitor with IC50 of 8 nM, equipotent against truncated p95-HER2, 500-fold more selective for HER2 versus EGFR.
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In Vitro——
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In Vivo——
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SynonymsARRY-380 analog | ONT380 analog | ONT 380 analog | ONT-380 analog
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PathwayAngiogenesis
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TargetEGFR
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RecptorEGFR| HER2| p95-HER2
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number937265-83-3
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Formula Weight569.63
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Molecular FormulaC29H27N7O4S
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Purity>98% (HPLC)
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SolubilityDMSO: > 10mM
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SMILESCC1=C(OC2=CC3=NC=NN3C=C2)C=CC(NC2=NC=NC3=C2C=C(C=C3)C2=CC=C(CNCCS(C)(=O)=O)O2)=C1
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Chemical Name6-[5-[[[2-(Methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]-4-quinazolinamine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Madala SK, et al. Am J Respir Cell Mol Biol. 2012 Mar;46(3):380-8.
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