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GSK1034702
CAS No. 932373-87-0
GSK1034702( GSK-1034702 | GSK 1034702 )
Catalog No. M16671 CAS No. 932373-87-0
GSK1034702 (GSK-1034702) is a potent, allosteric M1 receptor agonist, inhibits binding of [3H]-NMS (0.5 nM) to M1 mAChR with pKi of 6.5.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 155 | In Stock |
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| 10MG | 250 | In Stock |
|
| 25MG | 503 | In Stock |
|
| 50MG | 793 | In Stock |
|
| 100MG | 1190 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 2399 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameGSK1034702
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NoteResearch use only, not for human use.
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Brief DescriptionGSK1034702 (GSK-1034702) is a potent, allosteric M1 receptor agonist, inhibits binding of [3H]-NMS (0.5 nM) to M1 mAChR with pKi of 6.5.
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DescriptionGSK1034702 (GSK-1034702) is a potent, allosteric M1 receptor agonist, inhibits binding of [3H]-NMS (0.5 nM) to M1 mAChR with pKi of 6.5; improves memory encoding potentially by modulating hippocampal function.Other Indication Phase 1 Clinical.
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In Vitro——
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In Vivo——
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SynonymsGSK-1034702 | GSK 1034702
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PathwayGPCR/G Protein
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TargetmAChR
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RecptormAChR
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Research AreaOther Indications
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IndicationOther Disease
Chemical Information
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CAS Number932373-87-0
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Formula Weight333.407
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Molecular FormulaC18H24FN3O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 2 mg/mL
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SMILESc1ccc2c(c1)c(nn(c2=O)C[C@H]3CCCN3CCCCc4ccc(cc4)OCCCN5CCCCCC5)Cc6ccc(cc6)Cl
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Chemical Name7-fluoro-5-methyl-3-[1-(oxan-4-yl)piperidin-4-yl]-1H-benzimidazol-2-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Nathan PJ, et al. Int J Neuropsychopharmacol. 2013 May;16(4):721-31.
2. Bradley SJ, et al. Mol Pharmacol. 2018 Jun;93(6):645-656.
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