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Triazavirin
CAS No. 928659-17-0
Triazavirin( Riamilovir sodium dihydrate )
Catalog No. M16651 CAS No. 928659-17-0
Triazavirin (Riamilovir sodium dihydrate) is a broad-spectrum antiviral agent targeting influenza viruses, lassa virus, TBEV and Ebola virus.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 33 | In Stock |
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| 5MG | 31 | In Stock |
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| 10MG | 50 | In Stock |
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| 25MG | 89 | In Stock |
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| 50MG | 142 | In Stock |
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| 100MG | 211 | In Stock |
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| 200MG | 313 | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameTriazavirin
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NoteResearch use only, not for human use.
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Brief DescriptionTriazavirin (Riamilovir sodium dihydrate) is a broad-spectrum antiviral agent targeting influenza viruses, lassa virus, TBEV and Ebola virus.
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DescriptionTriazavirin (Riamilovir sodium dihydrate) is a broad-spectrum antiviral agent targeting influenza viruses, lassa virus, TBEV and Ebola virus; suppresses the replication of influenza virus in cell culture and in chicken chorioallantoic membranes, and protects mice from death caused by type A and B influenza viruses.(In Vitro):The efficacy of Triazavirin against the tick-borne encephalitis virus is estimated in the sensitive cell culture. In a concentration of 128 mcg/mL Triazavirin is shown active in inhibition of the tick-borne encephalitis virus reproduction (strain Sofiin) by accumulation in the SKEV cell culture.(In Vivo):The therapeutic efficacy Triazavirin against experimental Forest-Spring encephalitis on albino mice is studied. The results shows that in high doses (200-400 mg/kg) Triazavirin moderately protects the infected animals. A significant increase of the animal lifespan in the test groups (from 4.1 to 4.8 days) and a statistically valid decrease of the virus accumulation in the target organ are observed.
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In VitroThe efficacy of Triazavirin against the tick-borne encephalitis virus is estimated in the sensitive cell culture. In a concentration of 128 mcg/mL Triazavirin is shown active in inhibition of the tick-borne encephalitis virus reproduction (strain Sofiin) by accumulation in the SKEV cell culture.
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In VivoThe therapeutic efficacy Triazavirin against experimental Forest-Spring encephalitis on albino mice is studied. The results shows that in high doses (200-400 mg/kg) Triazavirin moderately protects the infected animals. A significant increase of the animal lifespan in the test groups (from 4.1 to 4.8 days) and a statistically valid decrease of the virus accumulation in the target organ are observed.
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SynonymsRiamilovir sodium dihydrate
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PathwayMicrobiology/Virology
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TargetInfluenza Virus
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RecptorInfluenza Virus
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Research Area——
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Indication——
Chemical Information
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CAS Number928659-17-0
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Formula Weight228.189
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Molecular FormulaC5H4N6O3S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (436.76 mM)
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SMILESCSC1=NN2C(=C(N=NC2=N1)[N+](=O)[O-])[O-].O.O.[Na+]
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Chemical Name7-(Methylthio)-3-nitro-[1,2,4]triazolo[5,1-c][1,2,4]triazin-4(6H)-one sodium sodium dihydrate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Karpenko I, et al. Antimicrob Agents Chemother. 2010 May;54(5):2017-22.
2. Loginova SIa, et al. Antibiot Khimioter. 2007;52(11-12):18-20.
3. Loginova SIa, et al. Antibiot Khimioter. 2014;59(1-2):3-5.
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