E-3030 free acid is a potent dual activator of peroxisome proliferator-activated receptor (PPAR) alpha and PPARgamma, exhibiting significant antidiabetic and lipid-modulating effects. E-3030 decreases blood glucose, triglyceride, non-esterified fatty acids, and insulin levels, while increasing blood adiponectin levels. E-3030 improves glucose tolerance and shows remarkable triglyceride- and non-high-density lipoprotein cholesterol-lowering effects in animal models.

Pamabron is a common over-the-counter diuretic used for relief of menstrual-associated symptoms.

Diclofenac methyl ester is a hydrophobic prodrug form of diclofenac which is a non-steroidal anti-inflammatory drug (NSAID).