Foxy-5

Research use only, not for human use.

Foxy-5 is a novel Wnt-5A mimicking hexapeptide that inhibits breast cancer metastasis in vivo by targeting cell motility.

Foxy-5 is a novel Wnt-5A mimicking hexapeptide that inhibits breast cancer metastasis in vivo by targeting cell motility; also significantly inhibits the initial metastatic dissemination of prostate cancer cells to regional and distal lymph nodes, specifically targets invasion without affecting apoptosis or viability of WNT5A-low prostate cancer cells. Breast Cancer Phase 1 Clinical.

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Foxy-5 effectively reduces the metastatic spread of WNT5A-low prostate cancer cells in an orthotopic mouse model.Foxy-5 reduces the number of colonic cancer stem cells in a xenograft mouse model of human colonic cancer.

formyl-Met-Asp-Gly-Cys-Glu-Leu | Foxy5

Wnt/Notch/Hedgehog

Wnt/beta/catenin

Wnt/beta/catenin

Cancer

Breast Cancer

881188-51-8

694.77

C26H42N6O12S2

>98% (HPLC)

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CC(C)C[C@@H](C(O)=O)NC([C@H](CCC(O)=O)NC([C@H](CS)NC(CNC([C@H](CC(O)=O)NC([C@H](CCSC)NC=O)=O)=O)=O)=O)=O

(2S,5S,8R,14S)-5-(2-carboxyethyl)-14-((S)-2-formamido-4-(methylthio)butanamido)-2-isobutyl-8-(mercaptomethyl)-4,7,10,13-tetraoxo-3,6,9,12-tetraazahexadecanedioic acid

(-20℃)

With Ice Pack

≥ 2 years