IKK-16 (IKK Inhibitor VII)( —— )

Catalog No. M16348 CAS No. 873225-46-8

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Datasheet

HNMR

HPLC

MSDS

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Product Name

IKK-16 (IKK Inhibitor VII)
Note

Research use only, not for human use.
Brief Description

IKK-16 (IKK Inhibitor VII) is a selective IκB kinase (IKK) inhibitor for IKK-2, IKK complex and IKK-1 with IC50 of 40 nM, 70 nM and 200 nM, respectively.
Description

IKK-16 (IKK Inhibitor VII) is a selective IκB kinase (IKK) inhibitor for IKK-2, IKK complex and IKK-1 with IC50 of 40 nM, 70 nM and 200 nM, respectively.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Immunology/Inflammation
Target

IκB kinase (IKK)
Recptor

IKK2| IKK1| IKK complex
Research Area

Cancer
Indication

——

CAS Number

873225-46-8
Formula Weight

483.63
Molecular Formula

C??H??N?OS
Purity

>98% (HPLC)
Solubility

DMSO:90 mg/mL (186.1 mM);Ethanol:<1 mg/mL;Water:<1 mg/mL
SMILES

O=C(N1CCC(CC1)N1CCCC1)C1=CC=C(NC2=NC=CC(=N2)C2=CC3=CC=CC=C3S2)C=C1 |c:22,24,31,33,38,t:15,17,20,27,29|
Chemical Name

——

1.Waelchli R, et al. Bioorg Med Chem Lett, 2006, 16(1), 108-112.

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