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Eluxadoline
CAS No. 864821-90-9
Eluxadoline( JNJ 27018966 | JNJ27018966 )
Catalog No. M16275 CAS No. 864821-90-9
A potent, selective, orally bioavailable μ-opioid receptor agonist and a δ-opioid receptor antagonist for the treatment of diarrhoea-predominant irritable bowel syndrome (IBS-D).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameEluxadoline
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, selective, orally bioavailable μ-opioid receptor agonist and a δ-opioid receptor antagonist for the treatment of diarrhoea-predominant irritable bowel syndrome (IBS-D).
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DescriptionA potent, selective, orally bioavailable μ-opioid receptor agonist and a δ-opioid receptor antagonist for the treatment of diarrhoea-predominant irritable bowel syndrome (IBS-D).Irritable Bowel Syndrome Approved.
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In Vitro——
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In Vivo——
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SynonymsJNJ 27018966 | JNJ27018966
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PathwayEndocrinology/Hormones
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TargetOpioid Receptor
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RecptorOpioid Receptor
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Research AreaOther Indications
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IndicationIrritable Bowel Syndrome
Chemical Information
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CAS Number864821-90-9
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Formula Weight569.651
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Molecular FormulaC32H35N5O5
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Purity>98% (HPLC)
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Solubility——
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SMILESCC1=CC(=CC(=C1C[C@@H](C(=O)N(CC2=CC(=C(C=C2)OC)C(=O)O)[C@@H](C)C3=NC=C(N3)C4=CC=CC=C4)N)C)C(=O)N
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Chemical Name5-(((S)-2-amino-3-(4-carbamoyl-2,6-dimethylphenyl)-N-((S)-1-(4-phenyl-1H-imidazol-2-yl)ethyl)propanamido)methyl)-2-methoxybenzoic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Dove LS, et al. Gastroenterology. 2013 Aug;145(2):329-38.e1.
2. Fujita W, et al. Biochem Pharmacol. 2014 Dec 1;92(3):448-56.
3. Davenport JM, et al. J Clin Pharmacol. 2015 May;55(5):534-42.
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