Setiptiline maleate( MO-8282 )

Catalog No. M16210 CAS No. 85650-57-3

A tetracyclic antidepressant (TeCA) that acts as a norepinephrine reuptake inhibitor, α2-adrenergic receptor antagonist, and serotonin receptor antagonist.

Purity : >98% (HPLC)

COA

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Biological Information

Product Name

Setiptiline maleate
Note

Research use only, not for human use.
Brief Description

A tetracyclic antidepressant (TeCA) that acts as a norepinephrine reuptake inhibitor, α2-adrenergic receptor antagonist, and serotonin receptor antagonist.
Description

A tetracyclic antidepressant (TeCA) that acts as a norepinephrine reuptake inhibitor, α2-adrenergic receptor antagonist, and serotonin receptor antagonist, as well as an H1 receptor inverse agonist/antihistamine.Depression Approved.
In Vitro

——
In Vivo

——
Synonyms

MO-8282
Pathway

GPCR/G Protein
Target

5-HT Receptor
Recptor

5-HT Receptor
Research Area

Neurological Disease
Indication

Depression

Chemical Information

CAS Number

85650-57-3
Formula Weight

377.433
Molecular Formula

C23H23NO4
Purity

>98% (HPLC)
Solubility

10 mM in DMSO
SMILES

CN1CCC2=C(C1)C3=CC=CC=C3CC4=CC=CC=C24.C(=CC(=O)O)C(=O)O
Chemical Name

1H-Dibenzo[3,4:6,7]cyclohepta[1,2-c]pyridine, 2,3,4,9-tetrahydro-2-methyl-, (2Z)-2-butenedioate (1:1)

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Niho T, et al. Nihon Yakurigaku Zasshi. 1986 Oct;88(4):309-20. 2. Mizota M, et al. Nihon Yakurigaku Zasshi. 1986 Dec;88(6):457-66. 3. Przegaliński E, et al. Pol J Pharmacol Pharm. 1986 Jul-Aug;38(4):377-84.

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