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Bedaquiline fumarate
CAS No. 845533-86-0
Bedaquiline fumarate( R403323 | TMC207 fumarate | R207910 fumarate )
Catalog No. M16140 CAS No. 845533-86-0
Bedaquiline fumarate (R403323, TMC207 fumarate, R207910 fumarate) is a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 67 | In Stock |
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| 5MG | 45 | In Stock |
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| 10MG | 68 | In Stock |
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| 25MG | 107 | In Stock |
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| 50MG | 144 | In Stock |
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| 100MG | 184 | In Stock |
|
| 200MG | 276 | In Stock |
|
| 500MG | 480 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBedaquiline fumarate
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NoteResearch use only, not for human use.
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Brief DescriptionBedaquiline fumarate (R403323, TMC207 fumarate, R207910 fumarate) is a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections.
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DescriptionBedaquiline fumarate (R403323, TMC207 fumarate, R207910 fumarate) is a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections.Bacterial Infection Approved.
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In Vitro——
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In Vivo——
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SynonymsR403323 | TMC207 fumarate | R207910 fumarate
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PathwayGPCR/G Protein
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TargetAntibacterial
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RecptorAntibacterial
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Research AreaInfection
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IndicationBacterial Infection
Chemical Information
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CAS Number845533-86-0
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Formula Weight671.588
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Molecular FormulaC36H35BrN2O6
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Purity>98% (HPLC)
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SolubilityDMSO : 100 mg/mL 148.90 mM; H2O : < 0.1 mg/mL
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SMILESCN(C)CCC(C1=CC=CC2=CC=CC=C21)(C(C3=CC=CC=C3)C4=C(N=C5C=CC(=CC5=C4)Br)OC)O.C(=CC(=O)O)C(=O)O
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Chemical Name(1R,2S)-1-(6-broMo-2-Methoxyquinolin-3-yl)-4-(diMethylaMino)-2-naphthalen-1-yl-1-phenylbutan-2-ol,(E)-but-2-enedioic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Jang JC, et al. J Microbiol. 2017 Apr 20.
2. Pang Y, et al. Antimicrob Agents Chemother. 2017 Apr 24;61(5).
3. Chahine EB, et al. Ann Pharmacother. 2014 Jan;48(1):107-15.
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