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WH-4-023

CAS No. 837422-57-8

WH-4-023( WH-4-023 | WH4-023 | WH 4-023 | WH-4023 )

Catalog No. M16103 CAS No. 837422-57-8

WH-4-023 is a potent and orally active Lck/Src inhibitor with IC50 of 2 nM and 6 nM in cell-free assays, respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 61 In Stock
10MG 91 In Stock
25MG 149 In Stock
50MG 186 In Stock
100MG 332 In Stock
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Biological Information

  • Product Name
    WH-4-023
  • Note
    Research use only, not for human use.
  • Brief Description
    WH-4-023 is a potent and orally active Lck/Src inhibitor with IC50 of 2 nM and 6 nM in cell-free assays, respectively.
  • Description
    WH-4-023 is a potent and orally active Lck/Src inhibitor with IC50 of 2 nM and 6 nM in cell-free assays, respectively.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    WH-4-023 | WH4-023 | WH 4-023 | WH-4023
  • Pathway
    Tyrosine Kinase
  • Target
    Src
  • Recptor
    Lck| Src
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    837422-57-8
  • Formula Weight
    568.67
  • Molecular Formula
    C32H36N6O4
  • Purity
    >98% (HPLC)
  • Solubility
    Ethanol: 6 mg/mL warmed (10.55 mM); DMSO: 12 mg/mL warmed (21.1 mM)
  • SMILES
    O=C(OC1=C(C)C=CC=C1C)N(C2=CC=C(OC)C=C2OC)C3=NC(NC4=CC=C(N5CCN(C)CC5)C=C4)=NC=C3
  • Chemical Name
    2,6-dimethylphenyl (2,4-dimethoxyphenyl)(2-((4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)carbamate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Martin MW, et al. J Med Chem. 2006 Aug 10;49(16): 4981-9
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