SR-57227

CAS No. 77145-51-8

SR-57227( SR 57227 | SR57227 )

Catalog No. M15916 CAS No. 77145-51-8

SR-57227 is a high affinity, selective 5-HT3 receptor agonist, demonstrates anticonvulsant effects in vivo.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 873 Get Quote
50MG 1782 Get Quote
100MG 2250 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    SR-57227
  • Note
    Research use only, not for human use.
  • Brief Description
    SR-57227 is a high affinity, selective 5-HT3 receptor agonist, demonstrates anticonvulsant effects in vivo.
  • Description
    SR-57227 is a high affinity, selective 5-HT3 receptor agonist, demonstrates anticonvulsant effects in vivo.Depression Discontinued.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    SR 57227 | SR57227
  • Pathway
    GPCR/G Protein
  • Target
    5-HT Receptor
  • Recptor
    5-HT Receptor
  • Research Area
    Neurological Disease
  • Indication
    Depression

Chemical Information

  • CAS Number
    77145-51-8
  • Formula Weight
    211.693
  • Molecular Formula
    C10H14ClN3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    NC1CCN(C2=NC(Cl)=CC=C2)CC1
  • Chemical Name
    1-(6-Chloro-2-pyridinyl)-4-piperidinamine

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Li B, et al. PLoS One. 2014 Apr 1;9(4):e93158. 2. Gholipour T, et al. Seizure. 2010 Jan;19(1):17-22. 3. Ortega JE, et al. Neuropharmacology. 2012 Jun;62(8):2472-9. 4. Guo W, et al. Mol Pain. 2014 Jun 9;10:35.
molnova catalog
related products
  • p-MPPF dihydrochlori...

    p-MPPF dihydrochloride is a selective 5-HT antagonist that dose-dependently antagonizes hypothermia induced by 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) and can be used to study neurological diseases.

  • Zalospirone

    Zalospirone is a 5-HT1A receptor agonist that can be used to study anxiety disorders and major depressive disorder.

  • 5HT6-ligand-1

    5HT6-ligand-1 is an orally active ligand of 5-HT6 receptor (Ki = 1.43 nM).