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Cefmenoxime hydrochloride
CAS No. 75738-58-8
Cefmenoxime hydrochloride( SCE-1365 )
Catalog No. M15880 CAS No. 75738-58-8
Cefmenoxime hydrochloride is a third-generation cephalosporin antibiotic.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 48 | In Stock |
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| 25MG | 30 | In Stock |
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| 50MG | 42 | In Stock |
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| 100MG | 60 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | 152 | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameCefmenoxime hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionCefmenoxime hydrochloride is a third-generation cephalosporin antibiotic.
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DescriptionCefmenoxime hydrochloride is a third-generation cephalosporin antibiotic.(In Vitro):Cefmenoxime (SCE-1365) hydrochloride inhibits at least 90% of strains tested (MIC90) ranged from 0.06 to 8 μg/mL for the Enterobacteriaceae.Cefmenoxime (SCE-1365) hydrochloride inhibits MIC90 values for gram-positive cocci are 0.015 and ≤0.008 μg/mL for Streptococcus pneumoniae and Streptococcus pyogenes, respectively, and 2 μg/mL for S. aureus.Cefmenoxime (SCE-1365) hydrochloride against Haemophilus influenzae, Neisseria gonorrhoeae, and Neisseria meningitidis with MIC90 values ranging from ≤0.008 to 0.25 μg/mL.(In Vivo):Cefmenoxime (SCE-1365) hydrochloride (40 mg/kg; i.h.; daily, for 7 d; male Jcl:ICR mice) improves the survival rate of mice infected with lung bacteria.
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In VitroCefmenoxime (SCE-1365) hydrochloride inhibits at least 90% of strains tested (MIC90) ranged from 0.06 to 8 μg/mL for the Enterobacteriaceae.Cefmenoxime (SCE-1365) hydrochloride inhibits MIC90 values for gram-positive cocci are 0.015 and ≤0.008 μg/mL for Streptococcus pneumoniae and Streptococcus pyogenes, respectively, and 2 μg/mL for S. aureus.Cefmenoxime (SCE-1365) hydrochloride against Haemophilus influenzae, Neisseria gonorrhoeae, and Neisseria meningitidis with MIC90 values ranging from ≤0.008 to 0.25 μg/mL.
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In VivoCefmenoxime (SCE-1365) hydrochloride (40 mg/kg; i.h.; daily, for 7 d; male Jcl:ICR mice) improves the survival rate of mice infected with lung bacteria. Animal Model:Male Jcl:ICR mice Dosage:40 mg/kg Administration: Subcutaneous injection; daily, for 7 days Result:Inhibited mortality rate of animals was 60% at a dose of 40 mg/kg.
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SynonymsSCE-1365
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PathwayGPCR/G Protein
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TargetAntibacterial
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RecptorPBPs| Fts1
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Research AreaInfection
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Indication——
Chemical Information
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CAS Number75738-58-8
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Formula Weight1059.58
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Molecular FormulaC32H35ClN18O10S6
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Purity>98% (HPLC)
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SolubilityDMSO: 8 mg/mL
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SMILESCN1N=NN=C1SCC2=C(N3C(=O)C(C3SC2)NC(=O)/C(=N/OC)/C4=CSC(=N4)N)C(=O)O.CN1N=NN=C1SCC2=C(N3C(=O)C(C3SC2)NC(=O)/C(=N/OC)/C4=CSC(=N4)N)C(=O)O.Cl
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Chemical Name7-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrochloride
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Tsuchiya K, et al. Antimicrob Agents ChemOthers. 1981 Jan;19(1):56-65.
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