Cart
sales@molnova.com
4-Methylpyrazole
CAS No. 7554-65-6
4-Methylpyrazole( 4-Methylpyrazole )
Catalog No. M15874 CAS No. 7554-65-6
Fomepizole is used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 48 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | 28 | In Stock |
|
| 500MG | 43 | In Stock |
|
| 1G | 45 | In Stock |
|
Biological Information
-
Product Name4-Methylpyrazole
-
NoteResearch use only, not for human use.
-
Brief DescriptionFomepizole is used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning.
-
DescriptionFomepizole is used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning. Fomepizole is a competitive inhibitor of alcohol dehydrogenase, the enzyme that catalyzes the initial steps in the metabolism of ethylene glycol and methanol to their toxic metabolites. (In Vivo):Pretreatment with Fomepizole (4-Methylpyrazole; 25 mg/kg; IP) prolongs ethanol neurobehavioral toxicity in CD-1 mice.
-
In Vitro——
-
In VivoPretreatment with Fomepizole (4-Methylpyrazole; 25 mg/kg; IP) prolongs ethanol neurobehavioral toxicity in CD-1 mice Animal Model:Male CD-1 mice weighing 18-25 gDosage:25 mg/kg Administration:IP; single dose Result:Decreased the dose of ethanol (1-5 g/kg; IP) at which 50% of the animals failed a particular outcome test (toxic dose 50; TD50).
-
Synonyms4-Methylpyrazole
-
PathwayEndocrinology/Hormones
-
TargetAChR
-
RecptorADH| CAT
-
Research AreaOther Indications
-
Indication——
Chemical Information
-
CAS Number7554-65-6
-
Formula Weight82.1
-
Molecular FormulaC4H6N2
-
Purity>98% (HPLC)
-
SolubilityWater: 146 mg/mL
-
SMILESCC1=CNN=C1
-
Chemical Name4-methyl-1H-pyrazole
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Nagata H, et al. Am J Physiol. 1996 Dec;271(6 Pt 1):G1028-33.
molnova catalog
related products
-
Tolterodine tartrate
Tolterodine Tartrate(PNU-200583E; Kabi-2234) is a potent muscarinic receptor antagonists that show selectivity for the urinary bladder over salivary glands in vivo.
-
Vinblastine sulfate
Vinblastine sulfate can inhibit the formation of microtubule, it also inhibit nAChR(IC50=8.9 uM).
-
4-Hydroxycoumarin
4-Hydroxycoumarin, a coumarin derivative.4-Hydroxycoumarin serves as an immediate precursor of 4-hydroxycoumarin (4HC) type anticoagulants (for example, warfarin).?4-Hydroxycoumarin derivatives ?are employed as the anticoagulant, antibacterial, antifungal, antiviral, antitumor, antiprotozoal, insecticidal, antimycobacterial, antimutagenic, antioxidant, anti-inflammatory agents, HIV protease inhibitors and tyrosine kinase inhibitors.
