3-Bromo-7-Nitroindazole( —— )

Catalog No. M15833 CAS No. 74209-34-0

3-Bromo-7-Nitroindazole is a more potent inhibitor of nNOS than 7-nitroindazole in vitro.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

3-Bromo-7-Nitroindazole
Note

Research use only, not for human use.
Brief Description

3-Bromo-7-Nitroindazole is a more potent inhibitor of nNOS than 7-nitroindazole in vitro.
Description

3-Bromo-7-Nitroindazole is a more potent inhibitor of nNOS than 7-nitroindazole in vitro, is also potent against iNOS, inhibits rat nNOS, bovine eNOS, and rat iNOS with IC50 of 0.17, 0.86, and 0.29 uM.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Immunology/Inflammation
Target

NOS
Recptor

NOS
Research Area

——
Indication

——

Chemical Information

CAS Number

74209-34-0
Formula Weight

242.032
Molecular Formula

C7H4BrN3O2
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (413.17 mM)
SMILES

C1=CC2=C(NN=C2C(=C1)[N+](=O)[O-])Br
Chemical Name

3-bromo-7-nitro-1H-indazole

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Gammie SC, et al. Brain Res. 2000 Jul 7;870(1-2):80-6. 2. Gocmez SS, et al. Pharmacol Biochem Behav. 2015 Apr;131:19-25. 3. Widdowson PS, et al. Br J Pharmacol. 1996 Apr;117(8):1761-7. 4. Vaupel DB, et al. Eur J Pharmacol. 1997 Apr 11;324(1):11-20.

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