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Elamipretide

CAS No. 736992-21-5

Elamipretide( SS-31 | MTP-131 | Bendavia )

Catalog No. M15818 CAS No. 736992-21-5

Elamipretide (SS-31, MTP-131, Bendavia) is a novel cell-permeable antioxidant tetrapeptide (D-Arg-dimethylTyr-Lys-Phe-NH2) that targets inner mitochondrial membrane and prevents oxidative damage of neuronal cells and other cell types.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 120 In Stock
10MG 187 In Stock
25MG 338 In Stock
50MG 506 In Stock
100MG 647 In Stock
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Biological Information

  • Product Name
    Elamipretide
  • Note
    Research use only, not for human use.
  • Brief Description
    Elamipretide (SS-31, MTP-131, Bendavia) is a novel cell-permeable antioxidant tetrapeptide (D-Arg-dimethylTyr-Lys-Phe-NH2) that targets inner mitochondrial membrane and prevents oxidative damage of neuronal cells and other cell types.
  • Description
    Elamipretide (SS-31, MTP-131, Bendavia) is a novel cell-permeable antioxidant tetrapeptide (D-Arg-dimethylTyr-Lys-Phe-NH2) that targets inner mitochondrial membrane and prevents oxidative damage of neuronal cells and other cell types; prevents mitochondrial depolarization, reduces islet cell apoptosis, increases islet cell yield, and improves posttransplantation function.Other Indication Phase 3 Clinical.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    SS-31 | MTP-131 | Bendavia
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Other Targets
  • Research Area
    Other Indications
  • Indication
    Other Disease

Chemical Information

  • CAS Number
    736992-21-5
  • Formula Weight
    639.802
  • Molecular Formula
    C32H49N9O5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : ≥ 29 mg/mL (45.33 mM)
  • SMILES
    O=C(N)[C@H](CC1=CC=CC=C1)NC([C@H](CCCCN)NC([C@H](CC2=C(C)C=C(O)C=C2C)NC([C@@H](CCCNC(N)=N)N)=O)=O)=O
  • Chemical Name
    (S)-6-amino-N-((S)-1-amino-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-((R)-2-amino-5-guanidinopentanamido)-3-(4-hydroxy-2,6-dimethylphenyl)propanamido)hexanamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Thomas DA, et al. J Am Soc Nephrol. 2007 Jan;18(1):213-22. 2. Zhao K, et al. Biochem Pharmacol. 2005 Dec 5;70(12):1796-806. 3. Mizuguchi Y, et al. Am J Physiol Renal Physiol. 2008 Nov;295(5):F1545-53.
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