Doxapram hydrochloride monohydrate

CAS No. 7081-53-0

Doxapram hydrochloride monohydrate( AHR 619 )

Catalog No. M15718 CAS No. 7081-53-0

Doxapram hydrochloride hydrate inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 410 nM, 37 μM, 9 μM, respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 28 In Stock
25MG 33 In Stock
50MG 48 In Stock
100MG 75 In Stock
200MG 110 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Doxapram hydrochloride monohydrate
  • Note
    Research use only, not for human use.
  • Brief Description
    Doxapram hydrochloride hydrate inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 410 nM, 37 μM, 9 μM, respectively.
  • Description
    Doxapram hydrochloride hydrate inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 410 nM, 37 μM, 9 μM, respectively.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    AHR 619
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    Potassium Channel
  • Recptor
    TASK-1| TASK-1/TASK-3 heterodimeric| TASK-3
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    7081-53-0
  • Formula Weight
    432.99
  • Molecular Formula
    C24H33ClN2O3
  • Purity
    >98% (HPLC)
  • Solubility
    Ethanol: 2 mg/mL (4.61 mM); Water: 25 mg/mL (57.73 mM); DMSO: 87 mg/mL (200.93 mM)
  • SMILES
    O=C1N(CC)CC(CCN2CCOCC2)C1(C3=CC=CC=C3)C4=CC=CC=C4.[H]Cl.[H]O[H]
  • Chemical Name
    2-Pyrrolidinone, 1-ethyl-4-(2-(4-morpholinyl)ethyl)-3,3-diphenyl-, monohydrochloride, monohydrate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Yost CS. CNS Drug Rev. 2006 Fall-Winter;12(3-4):236-49.
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