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Avobenzone
CAS No. 70356-09-1
Avobenzone( BMDBM | Butyl Methoxydibenzoylmethane )
Catalog No. M15703 CAS No. 70356-09-1
Avobenzone is an oil soluble ingredient used in sunscreen products to absorb the full spectrum of UVA rays and a dibenzoylmethane derivative.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 48 | In Stock |
|
| 100MG | 45 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 63 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAvobenzone
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NoteResearch use only, not for human use.
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Brief DescriptionAvobenzone is an oil soluble ingredient used in sunscreen products to absorb the full spectrum of UVA rays and a dibenzoylmethane derivative.
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DescriptionAvobenzone is an oil soluble ingredient used in sunscreen products to absorb the full spectrum of UVA rays and a dibenzoylmethane derivative.
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In VitroAvobenzone (EC50=14.1 μM) significantly promots adipogenesis in hBM-MSCs as its positive control obesogenic chemicals. Avobenzone (10 μM) significantly up-regulates mRNA levels of PPARγ during adipogenesis in hBM-MSCs.Avobenzone (1-50 μM; 48 hours) inhibits proliferative activities of human trophoblast cells.Avobenzone (1-50 μM; 48 hours) induces apoptosis in HTR8/SVneo cells.Avobenzone only shows weak ERa agonism and weak AR antagonism. Apoptosis Analysis Cell Line:HTR8/SVneo cells Concentration:1-50 μM Incubation Time:48 hours Result:Inhibited proliferative activities of HTR8/SVneo cells.
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In Vivo——
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SynonymsBMDBM | Butyl Methoxydibenzoylmethane
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number70356-09-1
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Formula Weight310.39
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Molecular FormulaC20H22O3
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Purity>98% (HPLC)
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SolubilityEthanol: 9 mg/mL (28.99 mM); DMSO: 62 mg/mL (199.74 mM)
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SMILESO=C(C1=CC=C(C(C)(C)C)C=C1)CC(C2=CC=C(OC)C=C2)=O
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Chemical Name1-(4-(tert-butyl)phenyl)-3-(4-methoxyphenyl)propane-1,3-dione
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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WDR5-0102
WDR5-0102 is a compound that inhibits the WDR5-MLL1 interface (K dis = 7 μM, K d = 4 μM), selectively reducing MLL1 HMT activity without affecting the human H3K4 methyltransferase SETD7 or other HMTs, including G9a, EHMT1, SUV39H2, SETD8, PRMT3, and PRMT5.
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ML-180
ML-180 is a potent orphan nuclear receptor liver receptor homolog 1 (LRH-1; NR5A2) inverse agonist (IC50 of 3.7 μM) .ML-180 (0.5-5 μM; 24 hours) shows a significant inhibition of cyclin-D1 and cyclin-E1 expression in hepatic cells, but has little effect on repression in SK-OV-3 cells[2]. ML-180 (5 μM; 24 hours) leads to a rapid decrease of LRH-1 expression and efficiently represses endogenous LRH-1 signaling.
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Kaempferol 3-O-sopho...
Kaempferol 3-O-sophoroside, a derivative of Kaempferol, is isolated from the leaves of cultivated mountain ginseng (Panax ginseng) with anti-inflammatory effects.
