Amlexanox

CAS No. 68302-57-8

Amlexanox( AA 673 | CHX 3673 | Elics )

Catalog No. M15611 CAS No. 68302-57-8

Amlexanox (AA673; CHX3673) is a specific inhibitor of IKKε and TBK1; inhibition of IKKε and TBK1 activity as determined by MBP phosphorylation showing an IC50 of approximately 1–2 μM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 48 In Stock
5MG 30 In Stock
25MG 52 In Stock
50MG 73 In Stock
100MG 90 In Stock
200MG Get Quote In Stock
500MG 217 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Amlexanox
  • Note
    Research use only, not for human use.
  • Brief Description
    Amlexanox (AA673; CHX3673) is a specific inhibitor of IKKε and TBK1; inhibition of IKKε and TBK1 activity as determined by MBP phosphorylation showing an IC50 of approximately 1–2 μM.
  • Description
    Amlexanox (AA673; CHX3673) is a specific inhibitor of IKKε and TBK1; inhibition of IKKε and TBK1 activity as determined by MBP phosphorylation showing an IC50 of approximately 1–2 μM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    AA 673 | CHX 3673 | Elics
  • Pathway
    Angiogenesis
  • Target
    FGFR
  • Recptor
    FGFR1| IL-3| Protein S100-P
  • Research Area
    Inflammation/Immunology
  • Indication
    ——

Chemical Information

  • CAS Number
    68302-57-8
  • Formula Weight
    298.29
  • Molecular Formula
    C16H14N2O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 100 mM
  • SMILES
    CC(C)C1=CC2=C(C=C1)OC3=NC(=C(C=C3C2=O)C(=O)O)N
  • Chemical Name
    2-amino-5-oxo-7-propan-2-ylchromeno[2,3-b]pyridine-3-carboxylic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Shishibori T, et al. Biochem J. 1999 Mar 15;338 ( Pt 3):583-9.
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