Cart
sales@molnova.com
Kif15-IN-1
CAS No. 672926-32-8
Kif15-IN-1( KIF15-IN-1 | KIF15IN-1 | KIF15-IN1 | KIF15IN1 | KIF15 IN 1 )
Catalog No. M15567 CAS No. 672926-32-8
Kif15-IN-1 is a potent, selective inhibitor of KIF15 motility, can act synergistically with Eg5 inhibitors to impair cancer cell proliferation.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 312 | In Stock |
|
| 50MG | 1341 | In Stock |
|
| 100MG | 1791 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameKif15-IN-1
-
NoteResearch use only, not for human use.
-
Brief DescriptionKif15-IN-1 is a potent, selective inhibitor of KIF15 motility, can act synergistically with Eg5 inhibitors to impair cancer cell proliferation.
-
DescriptionKif15-IN-1 is a potent, selective inhibitor of KIF15 motility, can act synergistically with Eg5 inhibitors to impair cancer cell proliferation.
-
In Vitro——
-
In Vivo——
-
SynonymsKIF15-IN-1 | KIF15IN-1 | KIF15-IN1 | KIF15IN1 | KIF15 IN 1
-
PathwayCytoskeleton/Cell Adhesion Molecules
-
TargetKinesin
-
RecptorKinesin
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number672926-32-8
-
Formula Weight430.479
-
Molecular FormulaC20H22N4O5S
-
Purity>98% (HPLC)
-
SolubilityDMSO : ≥ 100 mg/mL 232.30 mM; H2O : < 0.1 mg/mL
-
SMILESO=C(C1=C(C)N=C(NC([C@@H](N2C(NC3=C(C=CC=C3)C2=O)=O)C(C)C)=O)S1)OCC
-
Chemical Nameethyl (S)-2-(2-(2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl)-3-methylbutanamido)-4-methylthiazole-5-carboxylate
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Preparation of quinazolinediones as Kif15 kinesin inhibitors for treating cellular proliferative disorders. Pat. Appl. Publ. (2004), US 20040053948 A1 20040318.
2. Milic B, et al. Proc Natl Acad Sci U S A. 2018 Apr 27. pii: 201801242.
molnova catalog
related products
-
Kinesore
Kinesore is a small molecule activator of kinesin-1 that inhibits KLC2-SKIP interaction with IC50 of 101 uM, Ki of 49 uM.
-
Dimethylenastron
A small molecule inhibitor of the mitotic kinesin Eg5; inhibits endothelial cell proliferation and migration in vitro.
-
MK-0731
MK-0731 is a potent, selective kinesin spindle protein (KSP) inhibitor with IC50 of 2.2 nM, cell EC50 of 5.3 nM.
