2-NP

CAS No. 65182-56-1

2-NP( —— )

Catalog No. M15475 CAS No. 65182-56-1

2-NP increased the duration of STAT1 tyrosine phosphorylation in response to IFN-gamma, and this may underlie its enhancement of STAT1-dependent transcription.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 50 In Stock
10MG 87 In Stock
25MG 177 In Stock
50MG 282 In Stock
100MG 444 In Stock
200MG 646 In Stock
500MG 981 In Stock
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Biological Information

  • Product Name
    2-NP
  • Note
    Research use only, not for human use.
  • Brief Description
    2-NP increased the duration of STAT1 tyrosine phosphorylation in response to IFN-gamma, and this may underlie its enhancement of STAT1-dependent transcription.
  • Description
    2-NP increased the duration of STAT1 tyrosine phosphorylation in response to IFN-gamma, and this may underlie its enhancement of STAT1-dependent transcription. Reflecting the fact that STAT1 can exert tumor-suppressive effects, 2-NP enhanced the ability of IFN-gamma to inhibit the proliferation of human breast Y and fibrosarcoma cells.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    JAK/STAT Signaling
  • Target
    STAT
  • Recptor
    STAT1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    65182-56-1
  • Formula Weight
    222.24
  • Molecular Formula
    C14H10N2O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: > 10 mM
  • SMILES
    C1=C/C(=C/2\C=CC3=C(N2)N=CC=C3)/C(=O)C=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Lynch RA, et al. Y Res. 2007 Feb 1;67(3):1254-6
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