Thalidomide-O-amido-PEG-C2-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs.

Chaetoglobosin Fex from the marine-derived endophytic fungus inhibits induction of inflammatory mediators via Toll-like receptor 4 signaling in macrophages.

Phenylacetylglutamine is a normal constituent of human urine but other mammals such as the dog cat rat monkey sheep and horse do not excrete this compound. Phenylacetylglutamine is a major nitrogenous metabolite that accumulates in uremia. Phenylacetylglutamine also is a microbial metabolite found in Christensenellaceae Lachnospiraceae and Ruminococcaceae.