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Midazolam maleate

CAS No. 59467-94-6

Midazolam maleate( Dormicum | Versed )

Catalog No. M15207 CAS No. 59467-94-6

Midazolam (Dormicum;Versed) is a short-acting benzodiazepine derivative with anxiolytic, amnestic, hypnotic, anticonvulsant and sedative properties.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    Midazolam maleate
  • Note
    Research use only, not for human use.
  • Brief Description
    Midazolam (Dormicum;Versed) is a short-acting benzodiazepine derivative with anxiolytic, amnestic, hypnotic, anticonvulsant and sedative properties.
  • Description
    Midazolam (Dormicum;Versed) is a short-acting benzodiazepine derivative with anxiolytic, amnestic, hypnotic, anticonvulsant and sedative properties; exerts its effect by binding to the benzodiazepine receptor at GABA receptor-chloride ionophore complex in the central nervous system (CNS), leads to an increase in the opening of chloride channels, membrane hyperpolarization and increases the inhibitory effect of GABA in the CNS.Epilepsy Approved.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Dormicum | Versed
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    GAT
  • Recptor
    GAT
  • Research Area
    Neurological Disease
  • Indication
    Epilepsy

Chemical Information

  • CAS Number
    59467-94-6
  • Formula Weight
    441.843
  • Molecular Formula
    C22H17ClFN3O4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC1=NC=C2N1C3=C(C=C(C=C3)Cl)C(=NC2)C4=CC=CC=C4F.C(=CC(=O)O)C(=O)O
  • Chemical Name
    8-chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine maleate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Gerecke M.Br J Clin Pharmacol. 1983;16 Suppl 1:11S-16S. 2. Polc P, et al. Brain Res. 1981 Jul 27;217(1):216-20. 3. Stryker TD, et al. Brain Res. 1986 Jan 8;362(2):339-43. 4. Audi EA, et al. Eur J Pharmacol. 1984 Aug 17;103(3-4):279-85.
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