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Oligomycin A

CAS No. 579-13-5

Oligomycin A( MCH 32 )

Catalog No. M15123 CAS No. 579-13-5

Oligomycin A, created by Streptomyces, acts as a mitochondrial F0F1-ATPase inhibitor, with a Ki of 1 μM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Oligomycin A
  • Note
    Research use only, not for human use.
  • Brief Description
    Oligomycin A, created by Streptomyces, acts as a mitochondrial F0F1-ATPase inhibitor, with a Ki of 1 μM.
  • Description
    Oligomycin A, created by Streptomyces, acts as a mitochondrial F0F1-ATPase inhibitor, with a Ki of 1 μM; Oligomycin A shows anti-fungal activity.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    MCH 32
  • Pathway
    Endocrinology/Hormones
  • Target
    ATPase
  • Recptor
    Ki: 1 μM (F0F1-ATPase)
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    579-13-5
  • Formula Weight
    791.06
  • Molecular Formula
    C??H??O??
  • Purity
    >98% (HPLC)
  • Solubility
    N/A
  • SMILES
    O=C(/C=C/[C@@H](C)[C@H](O)[C@@H](C)C([C@@H](C)[C@H](O)[C@H]1C)=O)O[C@]([C@H]2C)([H])[C@@H](C)[C@]3(CC[C@@H](C)[C@@H](/C=C(O)/C)O3)O[C@]2([H])CC[C@H](CC)/C=C/C=C/C[C@H](C)[C@@H](O)[C@](C)(O)C1=O
  • Chemical Name
    (1S,2'R,4E,5'R,6R,6'S,7S,8R,10S,11S,12R,14S,15R,16S,18E,20E,22S,25R,28R,29S)-22-ethyl-3',4',5',6'-tetrahydro-7,11,14,15-tetrahydroxy-6'-[(1Z)-2-hydroxy-1-propen-1-yl]-5',6,8,10,12,14,16,28,29-nonamethyl-spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-[2H]pyran]-3,9,13-trione

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Salomon AR, et al. Apoptolidin, a selective cytotoxic agent, is an inhibitor of F0F1-ATPase. Chem Biol. 2001 Jan;8(1):71-80. 2. Ramió-Lluch L, et al. Oligomycin A-induced inhibition of mitochondrial ATP-synthase activity suppresses boar sperm motility and in vitro capacitation achievement without modifying overall sperm energy levels. Reprod Fertil Dev. 2014;26(6):883-97.
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