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Clozapine

CAS No. 5786-21-0

Clozapine( HF 1854 )

Catalog No. M15120 CAS No. 5786-21-0

An atypical antipsychotic agent that binds to 5-HT and dopamine receptor; is also potent at the α2-adrenoceptor with Ki of 51 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 37 In Stock
10MG 29 In Stock
25MG 42 In Stock
50MG 60 In Stock
100MG 90 In Stock
200MG 161 In Stock
500MG 296 In Stock
1G 440 In Stock
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Biological Information

  • Product Name
    Clozapine
  • Note
    Research use only, not for human use.
  • Brief Description
    An atypical antipsychotic agent that binds to 5-HT and dopamine receptor; is also potent at the α2-adrenoceptor with Ki of 51 nM.
  • Description
    An atypical antipsychotic agent that binds to 5-HT and dopamine receptor; is also potent at the α2-adrenoceptor with Ki of 51 nM; mainly used for schizophrenia.Schizophrenia Approved.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    HF 1854
  • Pathway
    GPCR/G Protein
  • Target
    Dopamine Receptor
  • Recptor
    D2|M1mAChR|α2-adrenoceptor
  • Research Area
    Neurological Disease
  • Indication
    Schizophrenia

Chemical Information

  • CAS Number
    5786-21-0
  • Formula Weight
    326.8233
  • Molecular Formula
    C18H19ClN4
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    CN1CCN(CC1)C2=C3C=CC=CC3=NC4=C(N2)C=C(C=C4)Cl
  • Chemical Name
    5H-Dibenzo[b,e][1,4]diazepine, 8-chloro-11-(4-methyl-1-piperazinyl)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Seeman P, et al. ACS Chem Neurosci. 2014 Jan 15;5(1):24-9. 2. Zhukovskaya NL, et al. Neurosci Lett. 2000 Jul 21;288(3):236-40. 3. Moreno JL, et al. Psychopharmacology (Berl). 2013 Jan;225(1):217-26.
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