Probenecid
CAS No. 57-66-9
Probenecid( NSC 18786 )
Catalog No. M15105 CAS No. 57-66-9
The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 46 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 34 | In Stock |
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| 1G | 47 | In Stock |
|
Biological Information
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Product NameProbenecid
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NoteResearch use only, not for human use.
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Brief DescriptionThe prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate.
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DescriptionThe prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
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In Vitro——
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In Vivo——
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SynonymsNSC 18786
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PathwayMembrane Transporter/Ion Channel
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TargetTRP/TRPV Channel
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RecptorTRPV2
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Research AreaMetabolic Disease
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Indication——
Chemical Information
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CAS Number57-66-9
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Formula Weight285.36
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Molecular FormulaC13H19NO4S
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Purity>98% (HPLC)
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SolubilityEthanol: 22 mg/mL (77.09 mM); DMSO: 57 mg/mL (199.74 mM)
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SMILESCCCN(CCC)S(=O)(=O)C1=CC=C(C=C1)C(=O)O
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Chemical Name4-(dipropylsulfamoyl)benzoic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Pyr6
Pyr6 is a selective TRPC3 inhibitor with IC50 of 0.49 uM(Ca2+ influx inhibition in thapsigargin depleted native RBL-2H3 cells).Pyr6 is an inhibitor of Ca2+ entry, which displays higher potency to inhibit Ca2+ entry mediated by CRAC channel than by TRPC3.Pyr3 is selective inhibitor of TRPC3, inhibited Orai1- and TRPC3-mediated Ca(2+) entry and currents as well as mast cell activation with similar potency.?
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M8-B Hydrochloride
M8-B Hydrochloride is a selective transient receptor potential melastatin-8 (TRPM8) channel antagonist.M8 B, a TRPM8 antagonist.
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JC-229
JC-229 is a potent and selective TbRPA1 inhibitor that can inhibit RPA1 in Trypanosoma brucei. JC-229 can be used to study human African Trypanosomiasis (HAT).
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