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Flupirtine

CAS No. 56995-20-1

Flupirtine( D-9998 )

Catalog No. M15076 CAS No. 56995-20-1

A selective neuronal potassium channel (KCNQ/KV7 channel) activator that also has indirect NMDA receptor antagonist and GABAA receptor modulatory properties.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Flupirtine
  • Note
    Research use only, not for human use.
  • Brief Description
    A selective neuronal potassium channel (KCNQ/KV7 channel) activator that also has indirect NMDA receptor antagonist and GABAA receptor modulatory properties.
  • Description
    A selective neuronal potassium channel (KCNQ/KV7 channel) activator that also has indirect NMDA receptor antagonist and GABAA receptor modulatory properties; a centrally acting non-opioid analgesic used as an analgesic for acute and chronic pain.Pain Discontinued.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    D-9998
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    Potassium Channel
  • Recptor
    Potassium Channel
  • Research Area
    Neurological Disease
  • Indication
    Pain

Chemical Information

  • CAS Number
    56995-20-1
  • Formula Weight
    304.3195
  • Molecular Formula
    C15H17FN4O2
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    CCOC(=O)NC1=C(N=C(C=C1)NCC2=CC=C(C=C2)F)N
  • Chemical Name
    Carbamic acid, N-[2-amino-6-[[(4-fluorophenyl)methyl]amino]-3-pyridinyl]-, ethyl ester

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Szelenyi I, et al. Inflamm Res. 2013 Mar;62(3):251-8. 2. Harish S, et al. J Anaesthesiol Clin Pharmacol. 2012 Apr;28(2):172-7. 3. Hedegaard ER, et al. J Pharmacol Exp Ther. 2016 Apr;357(1):94-102.
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