Cart
sales@molnova.com
ARC 239 dihydrochloride
CAS No. 55974-42-0
ARC 239 dihydrochloride( ARC-239 | ARC239 )
Catalog No. M15036 CAS No. 55974-42-0
A potent, selective α2B adrenoceptor antagonist with pKd of 8.8, 200-fold selectivity over α2A, and α2D receptors.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 32 | In Stock |
|
| 10MG | 45 | In Stock |
|
| 25MG | 96 | In Stock |
|
| 50MG | 152 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameARC 239 dihydrochloride
-
NoteResearch use only, not for human use.
-
Brief DescriptionA potent, selective α2B adrenoceptor antagonist with pKd of 8.8, 200-fold selectivity over α2A, and α2D receptors.
-
DescriptionA potent, selective α2B adrenoceptor antagonist with pKd of 8.8, 200-fold selectivity over α2A, and α2D receptors; competitively antagonizes pressor responses to adrenaline and inhibits pressor responses to noradrenaline, phenylephrine, tyramine, and dimethylphenylpiperazinium in rats and dogs.
-
In Vitro——
-
In Vivo——
-
SynonymsARC-239 | ARC239
-
PathwayAngiogenesis
-
TargetAdrenergic Receptor
-
RecptorAdrenergic Receptor
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number55974-42-0
-
Formula Weight480.43
-
Molecular FormulaC24H29N3O3.2HCl
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 125 mg/mL (260.18 mM)
-
SMILESCC1(C2=CC=CC=C2C(=O)N(C1=O)CCN3CCN(CC3)C4=CC=CC=C4OC)C.Cl.Cl
-
Chemical Name2-[2-(4-(2-Methoxyphenyl)piperazin-1-yl)ethyl]-4,4-dimethyl-1,3-(2H,4H)-isoquinolindione dihydrochloride
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Mouillé P, et al. J Cardiovasc Pharmacol. 1980;2(2):175-91.
2. Bylund D, et al. J Pharmacol Exp Ther. 1988 May;245(2):600-7.
3. Bylund DB, et al. J Pharmacol Exp Ther. 1989 Nov;251(2):640-4.
molnova catalog
related products
-
DL-Adrenaline Hydroc...
The active sympathomimetic hormone from the adrenal medulla in most species.
-
(R)-Terazosin
(R)-Terazosin is an active R-enantiomer of Terazosin. (R)-Terazosin is a potent antagonist of α1-adrenoceptor (α1a, α1b and α1d-adrenoceptor with Ki values of 6.51 nM, 1.01 nM and 1.97 nM, respectively).
-
Tolazoline
Tolazoline, a non-selective competitive α-adrenergic receptor antagonist, is used as a vasodilator to treat spasms of peripheral blood vessels.
