L-(-)-α-Methyldopa

CAS No. 555-30-6

L-(-)-α-Methyldopa( Methyldopa | MK-351 | NSC 169916 )

Catalog No. M15017 CAS No. 555-30-6

Methyldopa is an alpha-adrenergic agonist (selective for α2-adrenergic receptors) psychoactive drug used as a sympatholytic or antihypertensive.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 42 In Stock
100MG 28 In Stock
200MG Get Quote In Stock
500MG 47 In Stock
1G 65 In Stock

Biological Information

  • Product Name
    L-(-)-α-Methyldopa
  • Note
    Research use only, not for human use.
  • Brief Description
    Methyldopa is an alpha-adrenergic agonist (selective for α2-adrenergic receptors) psychoactive drug used as a sympatholytic or antihypertensive.
  • Description
    Methyldopa is an alpha-adrenergic agonist (selective for α2-adrenergic receptors) psychoactive drug used as a sympatholytic or antihypertensive.(In Vivo):Methyldopa hydrate (L-(-)-α-Methyldopa hydrate; 200 mg/kg; i.p.) decreases the hyperglycemic response in the first 2 hr after Dieldrin treatment.
  • In Vitro
    ——
  • In Vivo
    Methyldopa (L-(-)-α-Methyldopa; 200 mg/kg; i.p.) decreases the hyperglycemic response in the first 2 hr after Dieldrin treatment. Animal Model:60-day-old male rats Dosage:200 mg/kg Administration:I.p.Result: Decreased the plasma concentration of glucose in Dieldrin-exposed rats by 24% during the 30 min following its administration.
  • Synonyms
    Methyldopa | MK-351 | NSC 169916
  • Pathway
    GPCR/G Protein
  • Target
    Dopamine Receptor
  • Recptor
    DOPA decarboxylase
  • Research Area
    Cardiovascular Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    555-30-6
  • Formula Weight
    211.21
  • Molecular Formula
    C10H13NO4
  • Purity
    >98% (HPLC)
  • Solubility
    Ethanol: <1 mg/mL (<1 mM); Water: <1 mg/mL (<1 mM); DMSO: <1 mg/mL (<1 mM)
  • SMILES
    O=C(O)[C@@](C)(N)CC1=CC=C(O)C(O)=C1
  • Chemical Name
    (S)-2-amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Head GA. Ann N Y Acad Sci. 1999 Jun 21;881:279-86.
molnova catalog
related products
  • Nomifensine

    Nomifensine is a norepinephrine-dopamine reuptake inhibitor that prevents dopamine reuptake into synaptosomes.

  • 4,7-DIHYDROXYCOUMARI...

    4, 7-DIHYDROXYCOUMARIN is a bioactive natural compound.

  • MLS1547

    MLS1547 is a highly efficacious agonist of G protein-biased dopamine D2 receptor with a Ki of 1.2 μM. MLS1547 stimulates D2R G protein-mediated signaling with EC50 of 0.37 μM in a calcium mobilization assay.