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Acemetacin
CAS No. 53164-05-9
Acemetacin( Acemetacin | Rantudil | K 708 | K-708 | K708 )
Catalog No. M14887 CAS No. 53164-05-9
Acemetacin (Emflex) is a non-steroidal anti-inflammatory drug and a glycolic acid ester of indometacin that is a cyclooxygenase inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 29 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | 27 | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameAcemetacin
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NoteResearch use only, not for human use.
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Brief DescriptionAcemetacin (Emflex) is a non-steroidal anti-inflammatory drug and a glycolic acid ester of indometacin that is a cyclooxygenase inhibitor.
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DescriptionAcemetacin (Emflex) is a non-steroidal anti-inflammatory drug and a glycolic acid ester of indometacin that is a cyclooxygenase inhibitor.(In Vitro):Acemetacin (TVX 1322) is a non-steroidal anti-inflammatory drug, used for the treatment of osteoarthritis, rheumatoid arthritis, lower back pain, and relieving post-operative pain. Acemetacin (TVX 1322), a glycolic acid ester of indometacin, acts as a prodrug; in the body, it is metabolized to indometacin, which then acts as an inhibitor of cyclooxygenase, producing the anti-inflammatory effects. An advantage of Acemetacin (TVX 1322) is that it reduces gastric damage when compared to indometacin.
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In VitroAcemetacin (TVX 1322) is a non-steroidal anti-inflammatory drug, used for the treatment of osteoarthritis, rheumatoid arthritis, lower back pain, and relieving post-operative pain. Acemetacin (TVX 1322), a glycolic acid ester of indometacin, acts as a prodrug; in the body, it is metabolized to indometacin, which then acts as an inhibitor of cyclooxygenase, producing the anti-inflammatory effects. An advantage of Acemetacin (TVX 1322) is that it reduces gastric damage when compared to indometacin. From Wikipedia.
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In Vivo——
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SynonymsAcemetacin | Rantudil | K 708 | K-708 | K708
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PathwayChromatin/Epigenetic
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TargetCOX
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RecptorCOX
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Research AreaInflammation/Immunology
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Indication——
Chemical Information
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CAS Number53164-05-9
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Formula Weight415.82
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Molecular FormulaC21H18ClNO6
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Purity>98% (HPLC)
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SolubilityEthanol: 58 mg/mL warmed (139.48 mM); DMSO: 83 mg/mL (199.6 mM)
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SMILESO=C(OCC(O)=O)CC1=C(C)N(C(C2=CC=C(Cl)C=C2)=O)C3=C1C=C(OC)C=C3
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Chemical Name1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, carboxymethyl ester
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Chávez-Pi?a AE, et al. Br J Pharmacol, 2008, 155(6), 857-864.
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