Dimenhydrinate( NSC 117855 | NSC-117855 | NSC117855 | Dimenhydrinate | Dramalen | Dramamin )

Catalog No. M14850 CAS No. 523-87-5

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Get Quotation Bulk Inquiry Add to Cart

Product Name

Dimenhydrinate
Note

Research use only, not for human use.
Brief Description

Dimenhydrinate is an anti-emetic and anti-histamine commonly available over-the-counter as a motion sickness remedy.
Description

Dimenhydrinate is an anti-emetic and anti-histamine commonly available over-the-counter as a motion sickness remedy.
In Vitro

——
In Vivo

Animal Model:Male ICR mice (22-28 g)Dosage:3, 10, and 30 mg/kg Administration:IP; single dose Result:Significantly increased CPP scores (+105.4 s) compared to those of the vehicle-treated control group.
Synonyms

NSC 117855 | NSC-117855 | NSC117855 | Dimenhydrinate | Dramalen | Dramamin
Pathway

GPCR/G Protein
Target

Histamine Receptor
Recptor

H1 receptor
Research Area

Neurological Disease
Indication

——

CAS Number

523-87-5
Formula Weight

469.96
Molecular Formula

C24H28ClN5O3
Purity

>98% (HPLC)
Solubility

DMSO: 10 mM
SMILES

O=C(N1C)N(C)C2=C(NC(Cl)=N2)C1=O.CN(C)CCOC(C3=CC=CC=C3)C4=CC=CC=C4
Chemical Name

8-chloro-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione compound with 2-(benzhydryloxy)-N,N-dimethylethanamine (1:1)

1.Chen X, et al. Nucleic Acids Res. 2002, 30(1):412-5.

Calculator

molnova catalog