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Hesperidin
CAS No. 520-26-3
Hesperidin( Cirantin | Hesperidoside | NSC 44184 )
Catalog No. M14823 CAS No. 520-26-3
Hesperidin is a flavanone glycoside found abundantly in citrus fruits.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 48 | In Stock |
|
| 100MG | 56 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameHesperidin
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NoteResearch use only, not for human use.
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Brief DescriptionHesperidin is a flavanone glycoside found abundantly in citrus fruits.
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DescriptionHesperidin is a flavanone glycoside found abundantly in citrus fruits.
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In VitroCell Viability Assay Cell Line:MG-63 cells Concentration:0, 5, 25, 50, 100, 150, 200 μM Incubation Time:24, 48, 72 hours Result:Led to time-dependent and concentration-dependent cytotoxic effects, with IC50s of 94.3, 78.6 and 63.3 μM at 24, 48 and 72 h, respectively.Apoptosis Analysis Cell Line:MG-63 cells Concentration:0, 5, 50, 150 μM Incubation Time:48 hours Result:Increased the percentage of apoptotic cells from 4.7% to 17.9, 34.6 and 68.3% at the concentration of 0, 5, 50 and 150 μM, respectively.
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In Vivo——
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SynonymsCirantin | Hesperidoside | NSC 44184
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number520-26-3
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Formula Weight610.56
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Molecular FormulaC28H34O15
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Purity>98% (HPLC)
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SolubilityDMSO: 122 mg/mL (199.81 mM)
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SMILESO=C1C[C@@H](C2=CC=C(OC)C(O)=C2)OC3=C1C(O)=CC(O[C@@H]4O[C@H](CO[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O)=C3
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Chemical Name(2S)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxy-2,3-dihydrochromen-4-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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PKC ζ pseudosubstrat...
Inhibitor of protein kinase C (PKC) ζ; attached to cell permeabilisation Antennapedia domain vector peptide. Consists of amino acids 113 - 129 of PKC ζ pseudosubstrate domain linked by a disulphide bridge to the Antennapedia domain vector peptide. The Antennapedia peptide is actively taken up by intact cells, at 4 or 37°C, ensuring rapid and effective uptake of the inhibitor peptide. Once inside the cell, the disulphide bonds are subjected to reduction in the cytoplasm leading to release of the inhibitor peptide. Induces mast cell degranulation by a PKC ζ-independent pathway.
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NSI-189
NSI-189 is a nootropic and neurogenic research chemical derived from nicotinamide and pyrazine.
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GSTO1-IN-1
GSTO1-IN-1 is a potent glutathione S-transferase omega 1 inhibitor (GSTO1; IC50: 31 nM).
