Sclareol( Sclareol | )

Catalog No. M14787 CAS No. 515-03-7

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Sclareol
Note

Research use only, not for human use.
Brief Description

Sclareol, a labdane-type diterpene isolated from clary sage (Salvia sclarea), exerts growth inhibition and cytotoxic activity against a variety of human Y cell lines. Extracted from Salvia SclareL.
Description

Sclareol, a labdane-type diterpene isolated from clary sage (Salvia sclarea), exerts growth inhibition and cytotoxic activity against a variety of human Y cell lines. Extracted from Salvia SclareL. (In Vitro):Sclareol is cytotoxic to 13 of 14 human leukemia cell lines tested, with IC50 values ranging from 6.0–24.2 μg/mL, but is not cytotoxic to peripheral blood mononuclear leukocytes within the same dose range.
In Vitro

Sclareol is cytotoxic to 13 of 14 human?leukemia?cell lines tested, with IC50?values ranging from 6.0–24.2?μg/mL, but is not cytotoxic to peripheral blood mononuclear?leukocytes?within the same dose range.
In Vivo

——
Synonyms

Sclareol |
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

Other Indications
Indication

——

CAS Number

515-03-7
Formula Weight

308.51
Molecular Formula

C20H36O2
Purity

>98% (HPLC)
Solubility

Ethanol: 24 mg/mL warmed (77.79 mM); DMSO: 61 mg/mL warmed (197.73 mM)
SMILES

C[C@@](CC[C@H]1[C@](O)(CC[C@H]2C(C)(CCC[C@]12C)C)C)(C=C)O
Chemical Name

(1R,2R,4aS,8aS)-1-((R)-3-hydroxy-3-methylpent-4-en-1-yl)-2,5,5,8a-tetramethyldecahydronaphthalen-2-ol

1. Dimas K, et al. Biomed PharmacOthers, 2006, 60(3), 127-133.

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