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Dasolampanel

CAS No. 503294-13-1

Dasolampanel( NGX426 )

Catalog No. M14703 CAS No. 503294-13-1

Dasolampanel (NGX426) is an orally bioavailable, competitive antagonist of the AMPA-kainate receptors for the treatment of chronic pain conditions including neuropathic pain and migraine.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    Dasolampanel
  • Note
    Research use only, not for human use.
  • Brief Description
    Dasolampanel (NGX426) is an orally bioavailable, competitive antagonist of the AMPA-kainate receptors for the treatment of chronic pain conditions including neuropathic pain and migraine.
  • Description
    Dasolampanel (NGX426) is an orally bioavailable, competitive antagonist of the AMPA-kainate receptors for the treatment of chronic pain conditions including neuropathic pain and migraine.Migraine Discontinued.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    NGX426
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    iGluR
  • Recptor
    iGluR
  • Research Area
    Neurological Disease
  • Indication
    Migraine

Chemical Information

  • CAS Number
    503294-13-1
  • Formula Weight
    377.825
  • Molecular Formula
    C17H20ClN5O3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C1CC2CNC(CC2CC1OC3=C(C(=CC=C3)Cl)C4=NNN=N4)C(=O)O
  • Chemical Name
    (3S,4aS,6S,8aR)-6-(3-chloro-2-(1H-tetrazol-5-yl)phenoxy)-decahydroisoquinoline-3-carboxylic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Wallace MS, et al. Pain Med. 2012 Dec;13(12):1601-10. 2. Martinez-Perez JA, et al. Bioorg Med Chem Lett. 2013 Dec 1;23(23):6463-6.
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