Forsythin( —— )

Catalog No. M14639 CAS No. 487-41-2

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Product Name

Forsythin
Note

Research use only, not for human use.
Brief Description

Extracted from Forsythia suspensa;Suitability:The mixed solvent of chloroform and methanol,DMSO;Store the product in sealed,cool and dry condition.
Description

Extracted from Forsythia suspensa;Suitability:The mixed solvent of chloroform and methanol,DMSO;Store the product in sealed,cool and dry condition.(In Vitro):Phillyrin (1–5 μM; pretreatment 1 hour; 24 hours) inhibits high glucose-induced FAS protein significantly in HepG2 cells.Phillyrin (1–5 μM; pretreatment 1 hour; 24 hours) inhibits high glucose-induced FAS mRNA expression by suppressing SREBP-1c activation in human HepG2 hepatocytes.
In Vitro

Phillyrin (1–5 μM; pretreatment 1 hour; 24 hours) inhibits high glucose-induced FAS protein significantly in HepG2 cells.Phillyrin (1–5 μM; pretreatment 1 hour; 24 hours) inhibits high glucose-induced FAS mRNA expression by suppressing SREBP-1c activation in human HepG2 hepatocytes. RT-PCR Cell Line:Human HepG2 hepatocyte cells Concentration:1 μM; 2.5 μM; 5 μM Incubation Time:24 hours Result:Reduced FAS and SREBP-1c mRNA expression.
In Vivo

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Synonyms

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Pathway

MAPK/ERK Signaling
Target

p38 MAPK
Recptor

p38 MAPK
Research Area

Metabolic Disease
Indication

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1. Pan X, et al. Inflamm Res. 2014 Jul;63(7):597-608.

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