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(+)-Bicuculline
CAS No. 485-49-4
(+)-Bicuculline( NSC 32192 )
Catalog No. M14624 CAS No. 485-49-4
Bicuculline is a light-sensitive competitive antagonist of GABAA receptors. It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and several Corydalis species.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 48 | In Stock |
|
| 50MG | 59 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Name(+)-Bicuculline
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NoteResearch use only, not for human use.
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Brief DescriptionBicuculline is a light-sensitive competitive antagonist of GABAA receptors. It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and several Corydalis species.
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DescriptionBicuculline is a light-sensitive competitive antagonist of GABAA receptors. It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and several Corydalis species.
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In Vitro——
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In Vivo——
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SynonymsNSC 32192
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PathwayMembrane Transporter/Ion Channel
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TargetGAT
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RecptorGABAR
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Research AreaOther Indications
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Indication——
Chemical Information
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CAS Number485-49-4
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Formula Weight367.36
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Molecular FormulaC20H17NO6
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Purity>98% (HPLC)
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SolubilityDMSO: 73 mg/mL warmed (198.72 mM)
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SMILESO=C1O[C@@H]([C@H]2N(C)CCC3=CC4=C(OCO4)C=C23)C5=CC=C(OCO6)C6=C51
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Chemical Name(R)-6-((S)-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-[1,3]dioxolo[4,5-e]isobenzofuran-8(6H)-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Huang SH, et al. Eur J Pharmacol, 2003, 464(1), 1-8.
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