Anguizole

CAS No. 442666-98-0

Anguizole( Anguizole )

Catalog No. M14509 CAS No. 442666-98-0

Anguizole is a HCV NS4B inhibitor targeting second amphipathic helix of NS4B (NS4B-AH2).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Anguizole
  • Note
    Research use only, not for human use.
  • Brief Description
    Anguizole is a HCV NS4B inhibitor targeting second amphipathic helix of NS4B (NS4B-AH2).
  • Description
    Anguizole is a HCV NS4B inhibitor targeting second amphipathic helix of NS4B (NS4B-AH2), blocks genotype 1b HCV replication with EC50 of 310 nM; disrupts NS4B-AH2-mediated biological functions of NS4B, NS4B's dimerization/multimerization, its proper subcellular localization, as well as its interaction with NS5A.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Anguizole
  • Pathway
    Microbiology/Virology
  • Target
    HCV
  • Recptor
    HCV
  • Research Area
    Infection
  • Indication
    ——

Chemical Information

  • CAS Number
    442666-98-0
  • Formula Weight
    408.8078
  • Molecular Formula
    C17H11ClF2N4O2S
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    O=C(C1=NN2C(C(F)(Cl)F)=CC(C3=CC=CO3)=NC2=C1)NCC4=CC=CS4
  • Chemical Name
    Pyrazolo[1,5-a]pyrimidine-2-carboxamide, 7-(chlorodifluoromethyl)-5-(2-furanyl)-N-(2-thienylmethyl)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Choi M, et al. Virus Genes. 2013 Dec;47(3):395-407.
molnova catalog
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