Midodrine

CAS No. 42794-76-3

Midodrine( ±)-Midodrine )

Catalog No. M14451 CAS No. 42794-76-3

Midodrine is a selective α1-adrenoceptor agonist that acts as a vasopressor/antihypotensive agent for the treatment of dysautonomia and orthostatic hypotension.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 41 In Stock
5MG 37 In Stock
10MG 61 In Stock
25MG 100 In Stock
50MG 142 In Stock
100MG 213 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Midodrine
  • Note
    Research use only, not for human use.
  • Brief Description
    Midodrine is a selective α1-adrenoceptor agonist that acts as a vasopressor/antihypotensive agent for the treatment of dysautonomia and orthostatic hypotension.
  • Description
    Midodrine is a selective α1-adrenoceptor agonist that acts as a vasopressor/antihypotensive agent for the treatment of dysautonomia and orthostatic hypotension; activates the alpha-adrenergic receptors of the arteriolar and venous vasculature, producing an increase in vascular tone and elevation of blood pressure; does not stimulate cardiac beta-adrenergic receptors, and diffuses poorly across the blood-brain barrier.Hypertension Approved.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ±)-Midodrine
  • Pathway
    GPCR/G Protein
  • Target
    Adrenergic Receptor
  • Recptor
    Adrenergic Receptor
  • Research Area
    Cardiovascular Disease
  • Indication
    Hypertension

Chemical Information

  • CAS Number
    42794-76-3
  • Formula Weight
    254.2823
  • Molecular Formula
    C12H18N2O4
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    O=C(NCC(C1=CC(OC)=CC=C1OC)O)CN
  • Chemical Name
    Acetamide, 2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. McTavish D, et al. Drugs. 1989 Nov;38(5):757-77. 2. Pittner H, et al. Arzneimittelforschung. 1976;26(12):2145-54. 3. Kontani H, et al. Jpn J Pharmacol. 1992 Apr;58(4):339-46. 4. Brune ME, et al. J Urol. 2001 Oct;166(4):1555-9.
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