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Belinostat

CAS No. 414864-00-9

Belinostat ( PXD101 )

Catalog No. M14420 CAS No. 414864-00-9

Belinostat is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 39 In Stock
10MG 35 In Stock
25MG 56 In Stock
50MG 82 In Stock
100MG 121 In Stock
200MG 193 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    Belinostat
  • Note
    Research use only, not for human use.
  • Brief Description
    Belinostat is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity.
  • Description
    Belinostat is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity. Belinostat targets HDAC enzymes, thereby inhibiting tumor cell proliferation, inducing apoptosis, promoting cellular differentiation, and inhibiting angiogenesis. This agent may sensitize drug-resistant tumor cells to other antineoplastic agents, possibly through a mechanism involving the down-regulation of thymidylate synthase.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    PXD101
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    HDAC
  • Recptor
    HDAC
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    414864-00-9
  • Formula Weight
    318.35
  • Molecular Formula
    C15H14N2O4S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 64 mg/mL (201.03 mM)
  • SMILES
    C1=CC=C(C=C1)NS(=O)(=O)C2=CC=CC(=C2)/C=C/C(=O)NO
  • Chemical Name
    2-Propenamide, N-hydroxy-3-(3-((phenylamino)sulfonyl)phenyl)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Savickiene J, et al. anticancer Drugs. 2014 Sep;25(8):938-49.
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