Cart
sales@molnova.com
L-870810
CAS No. 410544-95-5
L-870810( L 870810 | L870810 )
Catalog No. M14410 CAS No. 410544-95-5
A potent, selective inhibitor of HIV integrase (IC50=8-15 nM) with potent antiviral activity in cell culture and good pharmacokinetic properties.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 963 | Get Quote |
|
| 50MG | 1962 | Get Quote |
|
| 100MG | 2520 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameL-870810
-
NoteResearch use only, not for human use.
-
Brief DescriptionA potent, selective inhibitor of HIV integrase (IC50=8-15 nM) with potent antiviral activity in cell culture and good pharmacokinetic properties.
-
DescriptionA potent, selective inhibitor of HIV integrase (IC50=8-15 nM) with potent antiviral activity in cell culture and good pharmacokinetic properties; exhibits broad-spectrum activity against WT and multidrug-resistant HIV-1, HIV-2, and SIV; orally bioavailable.
-
In Vitro——
-
In Vivo——
-
SynonymsL 870810 | L870810
-
PathwayMicrobiology/Virology
-
TargetHIV
-
RecptorHIV
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number410544-95-5
-
Formula Weight430.454
-
Molecular FormulaC20H19FN4O4S
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESO=C(C1=NC(N(CCCC2)S2(=O)=O)=C3C=CC=NC3=C1O)NCC4=CC=C(F)C=C4
-
Chemical Name5-(1,1-dioxothiazinan-2-yl)-N-[(4-fluorophenyl)methyl]-8-hydroxy-1,6-naphthyridine-7-carboxamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Hazuda DJ, et al. Proc Natl Acad Sci U S A. 2004 Aug 3;101(31):11233-8.
2. Zeng LF, et al. J Med Chem. 2012 Nov 26;55(22):9492-509.
3. Hombrouck A, et al. Antimicrob Agents Chemother. 2008 Jun;52(6):2069-78.
molnova catalog
related products
-
gp120-α4β7 binding i...
gp120-α4β7 binding inhibitor 11 is an anti-HIV agent. gp120-α4β7 binding inhibitor 11 interferes the binding of HIV associated glycoprotein gp12G with the integrin α4β7 (IC50=1.64nM).
-
Carrageenan
A linear sulfated polysaccharide extracted from red edible seaweeds, shows topical microbicide activity targeting HIV viruses.
-
NBD-11021
A small molecule, full antagonist of CD4 that blocks gp120-CD4 interaction.
