Cart
sales@molnova.com
Home - Products - Microbiology/Virology - HIV - L-870810

L-870810

CAS No. 410544-95-5

L-870810( L 870810 | L870810 )

Catalog No. M14410 CAS No. 410544-95-5

A potent, selective inhibitor of HIV integrase (IC50=8-15 nM) with potent antiviral activity in cell culture and good pharmacokinetic properties.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 963 Get Quote
50MG 1962 Get Quote
100MG 2520 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    L-870810
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent, selective inhibitor of HIV integrase (IC50=8-15 nM) with potent antiviral activity in cell culture and good pharmacokinetic properties.
  • Description
    A potent, selective inhibitor of HIV integrase (IC50=8-15 nM) with potent antiviral activity in cell culture and good pharmacokinetic properties; exhibits broad-spectrum activity against WT and multidrug-resistant HIV-1, HIV-2, and SIV; orally bioavailable.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    L 870810 | L870810
  • Pathway
    Microbiology/Virology
  • Target
    HIV
  • Recptor
    HIV
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    410544-95-5
  • Formula Weight
    430.454
  • Molecular Formula
    C20H19FN4O4S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(C1=NC(N(CCCC2)S2(=O)=O)=C3C=CC=NC3=C1O)NCC4=CC=C(F)C=C4
  • Chemical Name
    5-(1,1-dioxothiazinan-2-yl)-N-[(4-fluorophenyl)methyl]-8-hydroxy-1,6-naphthyridine-7-carboxamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hazuda DJ, et al. Proc Natl Acad Sci U S A. 2004 Aug 3;101(31):11233-8. 2. Zeng LF, et al. J Med Chem. 2012 Nov 26;55(22):9492-509. 3. Hombrouck A, et al. Antimicrob Agents Chemother. 2008 Jun;52(6):2069-78.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Apelin-36 (rat, mous...

    Endogenous APJ receptor agonist that is secreted by adipocytes. Binds with high affinity to APJ receptors (IC50 = 5.4 nM) and potently inhibits cAMP production in vitro (EC50 = 0.52 nM). Involved in regulation of cardiovascular function, fluid homeostasis and feeding. Blocks entry of some HIV-1 and HIV-2 strains into NP-2/CD4 cells expressing APJ.

  • Apelin-36 (human)

    Endogenous APJ receptor agonist (EC50 = 20 nM) that is secreted by adipocytes. Binds with high affinity to human APJ receptors expressed in HEK 293 cells (pIC50= 8.61). Involved in regulation of cardiovascular function, fluid homeostasis and feeding. Blocks entry of some HIV-1 and HIV-2 strains into NP-2/CD4 cells expressing APJ.

  • HIV gag peptide 197-...

    HIV gag peptide (197-205) is a H-2Kd-restricted epitope derived from the p24 portion of the HIV-1 gag protein and composed of the amino acid 197-205 (AMQMLKETI).

Sign In Join Free